Here are our NFL picks for Monday 28 September 2026. Our model likes 6 bets here. Here is the thinking behind each pick, in plain English.

San Francisco 49ers vs Arizona Cardinals: San Francisco 49ers (+115)

Odds available at DraftKings at time of publishing

San Francisco 49ers play Arizona Cardinals in the NFL on Sunday 27 September 2026. The bet we are looking at is San Francisco 49ers. It was priced at +115 when we wrote this, so a $10 bet returns $21.50 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Chicago Bears vs Philadelphia Eagles: Over (-105)

Odds available at DraftKings at time of publishing

Chicago Bears play Philadelphia Eagles in the NFL on Tuesday 29 September 2026. The bet we are looking at is Over. It was priced at -105 when we wrote this, so a $10 bet returns $19.50 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

New York Giants vs Tennessee Titans: New York Giants (-128)

Odds available at FanDuel at time of publishing

New York Giants play Tennessee Titans in the NFL on Sunday 27 September 2026. The bet we are looking at is New York Giants. That is a Team Total bet. It was priced at -128 when we wrote this, so a $10 bet returns $17.80 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

New Orleans Saints vs Las Vegas Raiders: Las Vegas Raiders (-108)

Odds available at DraftKings at time of publishing

New Orleans Saints play Las Vegas Raiders in the NFL on Sunday 27 September 2026. The bet we are looking at is Las Vegas Raiders. It was priced at -108 when we wrote this, so a $10 bet returns $19.30 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

New Orleans Saints vs Las Vegas Raiders: Las Vegas Raiders (+136)

Odds available at DraftKings at time of publishing

New Orleans Saints play Las Vegas Raiders in the NFL on Sunday 27 September 2026. The bet we are looking at is Las Vegas Raiders. It was priced at +136 when we wrote this, so a $10 bet returns $23.60 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

New Orleans Saints vs Las Vegas Raiders: Over (-110)

Odds available at FanDuel at time of publishing

New Orleans Saints play Las Vegas Raiders in the NFL on Sunday 27 September 2026. The bet we are looking at is Over. It was priced at -110 when we wrote this, so a $10 bet returns $19.10 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

That is the model's read on today's NFL card. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.

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