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NFL Week 1 Predictions & Best Bets

Our model's one best bet for every NFL game in week 1 (Sep 10–14) — plain English, real prices, and every pick graded in public afterwards.

New England Patriots at Seattle Seahawks

Wed Sep 9, 8:20 PM ET
Our pick: Seattle Seahawks (moneyline 3 way q1)+110

LEAN — about a 1 in 2 chance by our numbers

San Francisco 49ers at Los Angeles Rams

Thu Sep 10, 8:35 PM ET
Our pick: Los Angeles Rams -0.5 (spreads q1)+110

LEAN — about a 1 in 2 chance by our numbers

Atlanta Falcons at Pittsburgh Steelers

Sun Sep 13, 1:00 PM ET
Our pick: Pittsburgh Steelers -3 (point spread)-115

HIGH — about a 1 in 1 chance by our numbers

New York Jets at Tennessee Titans

Sun Sep 13, 1:00 PM ET
Our pick: Tennessee Titans -2.5 (point spread)-105

HIGH — about a 1 in 1 chance by our numbers

Chicago Bears at Carolina Panthers

Sun Sep 13, 1:00 PM ET
Our pick: Chicago Bears -2.5 (point spread)-118

LEAN — about a 1 in 2 chance by our numbers

Tampa Bay Buccaneers at Cincinnati Bengals

Sun Sep 13, 1:00 PM ET
Our pick: Cincinnati Bengals -3.5 (point spread)-110

HIGH — about a 1 in 1 chance by our numbers

New Orleans Saints at Detroit Lions

Sun Sep 13, 1:00 PM ET
Our pick: Over 49.5 (total points)-105

LEAN — about a 1 in 2 chance by our numbers

Buffalo Bills at Houston Texans

Sun Sep 13, 1:00 PM ET
Our pick: Over 44.5 (total points)-110

LEAN — about a 1 in 2 chance by our numbers

Baltimore Ravens at Indianapolis Colts

Sun Sep 13, 1:00 PM ET
Our pick: Baltimore Ravens -3.5 (point spread)-112

LEAN — about a 1 in 2 chance by our numbers

Cleveland Browns at Jacksonville Jaguars

Sun Sep 13, 1:00 PM ET
Our pick: Cleveland Browns (to win)+300

LONG-SHOT — about a 1 in 4 chance by our numbers

Miami Dolphins at Las Vegas Raiders

Sun Sep 13, 4:25 PM ET
Our pick: Las Vegas Raiders -3.5 (point spread)-110

HIGH — about a 1 in 1 chance by our numbers

Arizona Cardinals at Los Angeles Chargers

Sun Sep 13, 4:25 PM ET
Our pick: Arizona Cardinals (to win)+400

LONG-SHOT — about a 1 in 4 chance by our numbers

Washington Commanders at Philadelphia Eagles

Sun Sep 13, 4:25 PM ET
Our pick: Philadelphia Eagles -4.5 (point spread)-110

HIGH — about a 1 in 1 chance by our numbers

Green Bay Packers at Minnesota Vikings

Sun Sep 13, 4:25 PM ET
Our pick: Under 45.5 (total points)-110

HIGH — about a 1 in 2 chance by our numbers

Dallas Cowboys at New York Giants

Sun Sep 13, 8:20 PM ET
Our pick: Under 23.5 (totals h2)-110

LEAN — about a 1 in 2 chance by our numbers

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Questions people ask

What are the best NFL bets for week 1?

Our model picked one best bet in each of the 15 games it priced for week 1 (Sep 10–14). They are all on this page with the price and how confident the model is, in plain words.

Are these picks free?

Yes. Every pick on this page is free, no signup. We grade every published pick in public afterwards — wins and losses.

When do NFL week 1 picks come out?

A day or two before each game, once the betting markets for it are priced. The page fills up across the week (Sep 10–14).

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