Here are our NFL picks for Tuesday 15 September 2026. Our model likes 6 bets here. The one it likes most is Dalton Kincaid (BUF) Over 3.5 Receptions, priced at -161 when we wrote this. Here is the thinking behind each pick, in plain English.

Dalton Kincaid (BUF) Over 3.5 Receptions (-161)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Dalton Kincaid (BUF) Over 3.5 Receptions. It was priced at -161 when we wrote this, so a $10 bet returns $16.20 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Dalton Kincaid (BUF) Over 3.5 Receptions (-167)

Odds available at DraftKings at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Dalton Kincaid (BUF) Over 3.5 Receptions. It was priced at -167 when we wrote this, so a $10 bet returns $16.00 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Khalil Shakir (BUF) Under 45.5 Receiving Yards (-111)

Odds available at DraftKings at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Khalil Shakir (BUF) Under 45.5 Receiving Yards. It was priced at -111 when we wrote this, so a $10 bet returns $19.00 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Khalil Shakir (BUF) Under 44.5 Receiving Yards (-114)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Khalil Shakir (BUF) Under 44.5 Receiving Yards. It was priced at -114 when we wrote this, so a $10 bet returns $18.80 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

DJ Moore (BUF) Under 4.5 Receptions (-112)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is DJ Moore (BUF) Under 4.5 Receptions. It was priced at -112 when we wrote this, so a $10 bet returns $18.90 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

DJ Moore (BUF) Under 4.5 Receptions (-116)

Odds available at DraftKings at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is DJ Moore (BUF) Under 4.5 Receptions. It was priced at -116 when we wrote this, so a $10 bet returns $18.60 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

That is the model's read on today's NFL card. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.

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