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NFL
Sun 25 Oct 2026, 4:05PM ET
Denver Broncos
3-2 · 1-2 awayLWWLW
VS
Arizona Cardinals
1-4 · 0-2 at homeWLLLL

Denver Broncos vs Arizona Cardinals prediction and odds · Sun 25 Oct

Arizona Cardinals host Denver Broncos on Sunday 25 October.

Sunday 25 October 2026: Denver Broncos at Arizona Cardinals

Arizona Cardinals host Denver Broncos on Sunday 25 October. The bookies' prices make the Broncos about a 7 in 10 chance to win. Our model's pick lands about 5 days before kickoff.
How they've been scoring this season
Denver BroncosArizona Cardinals
Won-lost3-21-4
Points scored per game19.421.6
Points allowed per game22.232.4
On the road / at home1-2 away0-2 at home
Last 5 gamesLWWLWWLLLL
Their games average 47.8 total points this season.
From the 5 Denver Broncos and 5 Arizona Cardinals games on our books this season.

Denver Broncos vs Arizona Cardinals odds

Prices for this game

Best price: Cardinals pay $3.00, Broncos pay $1.44 (the best of 8 bookies we checked). $100 on the Broncos returns $144.

Fair chance (our read of the prices, with the bookies' cut taken out): Cardinals about 3 in 10, Broncos about 7 in 10.

How much the bookies keep: about $4.34 of every $100 bet on this game.

Since betting opened: the price has barely moved.

Our pick for this game

Our model's pick lands about 5 days before kickoff. Today's NFL picks are already up: see today's NFL picks.

Injuries & who's out

Injuries & availability

Denver Broncos

  • Riley Moss CBQuestionable
  • Pat Surtain II CBOut
  • Talanoa Hufanga SOut
  • Pat Bryant WROut

Arizona Cardinals

  • Wydett Williams Jr. SOut
  • Kitan Crawford SOut
  • Andrew Wingard SQuestionable
  • Devin Duvernay WRQuestionable
  • Jeremiyah Love RBQuestionable
  • James Conner RBOut
  • Isaiah Adams GOut
Availability updated Oct 15, 1:25AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Denver Broncos vs Arizona Cardinals head-to-head record

Final scores · 2 meetings on record
Denver Broncos 2–0 across the last 2 meetings (meetings on record since 2018)

Last meeting: Sun 18 Dec 2022, Arizona Cardinals at Denver Broncos: the Broncos won 24-15.

DateGameScoreWinner
18 Dec 2022Arizona Cardinals @ Denver Broncos24–15Denver Broncos
18 Oct 2018Denver Broncos @ Arizona Cardinals10–45Denver Broncos

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