Here are our Serie A picks for Sunday 20 September 2026. Our model likes 6 bets here. The one it likes most is Lecce +1.75 Goal Handicap, priced at -120 when we wrote this. Here is the thinking behind each pick, in plain English.

AC Milan vs Lecce: Lecce +1.75 Goal Handicap (-120)

Odds available at DraftKings at time of publishing

As AC Milan gears up to host Lecce, the dynamics point toward an intriguing clash. Milan's home form has been shaky, with just two wins in their last five at San Siro, averaging a mere 1 goal per game. Their defensive woes are evident, as they've conceded 1.6 goals per home match recently. Meanwhile, Lecce is riding a wave of momentum, clinching three wins in their last five outings, scoring 1.4 goals per match on the road. Their recent head-to-head history tilts heavily in Milan's favor, but the tides may be turning. Lecce is tougher than their record suggests. With a handicap of 1.75, backing Lecce feels like a savvy play, especially if they can exploit Milan’s defensive vulnerabilities. Expect a spirited performance from the visitors, making this bet an enticing prospect for those looking to capitalize on recent trends.

Fiorentina vs Napoli: Over 9.5 Total Corners (+160)

Odds available at FanDuel at time of publishing

As Fiorentina prepares to host Napoli, the scene is set for a corner-filled showdown. Recent matches suggest a surge in corner activity, especially with Fiorentina averaging over 17 shots at home but struggling to convert those into goals—scoring just 0.4 in their last five home outings. This indicates a tendency to attack but fall short in finishing, leading to more corner opportunities. On the flip side, Napoli has been effective on the road, averaging 13.4 shots and a solid 1.6 goals per game. Their ability to push the pace creates an environment ripe for corners. Given the home team’s struggles and Napoli’s attacking prowess, expecting over 9.5 corners feels like a reasonable bet, especially as both teams aim to capitalize on their offensive styles. The statistical trends lean heavily in favor of a corner bonanza this Sunday.

Fiorentina vs Napoli: Over 8.5 Total Corners (-108)

Odds available at FanDuel at time of publishing

As Fiorentina welcomes Napoli, the stage is set for an action-packed encounter that’s likely to see plenty of corners. Fiorentina, despite their recent struggles at home—averaging just 0.4 goals and 17 shots in their last five home games—tends to push forward aggressively, leading to a high volume of corner kicks. Napoli, on the other hand, has been in solid form, averaging 1.6 goals and generating around 13.4 shots per away match. Their ability to exploit space means they’ll likely test Fiorentina's defense frequently, resulting in more corners for both sides. With Fiorentina averaging 15.6 shots per game overall and Napoli's propensity to create chances, the likelihood of hitting over 8.5 corners is compelling. Expect both teams to contribute to a flurry of corners in a match that could see tactical battles and attacking flair unfold.

Fluminense vs Coritiba: Both Teams To Score: No (-143)

Odds available at williamhill at time of publishing

As Fluminense prepares to host Coritiba, the expectation for a low-scoring affair seems justified. Recent matchups reveal that both teams are struggling to convert chances, with Fluminense averaging just 1.4 goals at home while only allowing 0.8. Their defense has been particularly solid, reflected in their record of just two goals conceded across five home games. Coritiba’s away form paints a similar picture; they’ve averaged 1.4 goals but have only mustered a mere 1.2 against opponents on the road. With Fluminense’s defensive prowess and Coritiba's inability to consistently find the net, the likelihood of both teams scoring feels slim. The xG numbers further emphasize this trend, as both squads have failed to create significant threats recently. In a game where defenses may well overshadow the attacks, betting on 'No' for both teams to score looks like a sound approach.

AC Milan vs Lecce: Lecce +1.5 Goal Handicap (+104)

Odds available at FanDuel at time of publishing

As AC Milan prepares to host Lecce, recent form and statistics suggest Lecce could surprise. While Milan boasts an impressive head-to-head record, they’ve been shaky lately, managing just two wins in their last five outings, including a lackluster home performance where they average only 1 goal per game. Their xG numbers reflect struggles, too—just 0 in their last home matches, indicating a worrying trend. In contrast, Lecce comes in with a strong away record, having scored an average of 1.4 goals in their last five road games. They’ve shown resilience with three wins in their last five overall, and their ability to create chances could exploit Milan's defensive vulnerabilities. With Lecce’s handicap of +1.5 looking favorable, this matchup presents an enticing opportunity for a thoughtful wager on Lecce to either lose by one or pull off an upset.

AC Milan vs Lecce: Lecce +1.25 Goal Handicap (+145)

Odds available at DraftKings at time of publishing

As AC Milan prepares to host Lecce, recent form leans in favor of the visitors. Lecce has found their groove, securing three wins in their last five outings, while Milan's home form has been shaky, with just two wins from their last five matches. The Rossoneri have struggled to convert chances, averaging only 1.6 goals per game while conceding 1.2. In contrast, Lecce's away performance has been commendable, netting 1.4 goals per game and allowing only 0.8. With Milan’s historical dominance over Lecce fading—having gone 5-0-0 recently against them—this match promises to be a tighter contest than expected. Lecce’s attacking prowess, coupled with Milan's home struggles, makes the 1.25 handicap on Lecce a tantalizing prospect. Expect an exciting clash where Lecce could very well keep things competitive, if not snatch a point.

That is the model's read on today's Serie A card. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.

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