Detroit Tigers vs Pittsburgh Pirates Prediction and Picks, September 27, 2026

The Detroit Tigers have struggled lately, winning just 2 of their last 6 games. However, they're playing at home, where they typically feel more comfortable. Facing the Pittsburgh Pirates, who have trouble hitting home runs at Comerica Park, gives the Tigers a solid chance to pull out a win. The Tigers' recent performance might not be great, but the Pirates' power issues could limit their scoring. With odds at +118, a win for Detroit isn't guaranteed, but it feels like a good spot for them to break through.

Detroit Tigers vs Pittsburgh Pirates: Over 9.5 Total Runs (+190)

The Tigers have had a tough time lately, winning only 1 of their last 5 games, but they are at home in Comerica Park, which can help boost their performance. The Pirates tend to keep home runs down at PNC Park, so the Tigers might find it easier to score runs against them at home, especially with their lineup looking to bounce back. With a total runs line set at 9.5, this bet feels like a good chance. Even though our numbers suggest a combined total of about 8.7, both teams can put runs on the board when they need to. The biggest risk here is the Pirates' ability to limit runs, but the Tigers could surprise us at home.

That is the full board for this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.