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Model picks & player props
MLB
Minute Maid Park, Houston
Indoor
Sun 19 Apr 2026, 2:10 PM ET
St. Louis Cardinals
VS
Houston Astros

St. Louis Cardinals vs Houston Astros Prediction & Picks

Our model graded 13 markets for St. Louis Cardinals vs Houston Astros and backs St. Louis Cardinals hardest, a lean, and $100 on it returns about $223.

13
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first Free
St. Louis Cardinals
to win
St. Louis Cardinals Moneyline
You bet$10 If it wins$22.30Best price+123
Our confidenceLean
Chance to win52.8%
The price says44.8%

The model graded 13 markets for St. Louis Cardinals vs Houston Astros (MLB) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $223 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 19 Apr 2026, 2:10 PM ET at Minute Maid Park.

This game's bets

The rest of this game's boardgraded market by market
Moneyline St. Louis Cardinals Lean53% chance +123
Spread Members only High63% chance Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%

St. Louis Cardinals and Houston Astros last met on Sun 19 Apr 2026: St. Louis Cardinals won 7-5. Their next game gets a fresh preview here the moment it is priced. Today's board: every MLB game priced right now.

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Game picks

GOOD PRICE in green
Moneyline
St. Louis Cardinals
+ 12 more markets
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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
St. Louis CardinalsMoneylineThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
St. Louis CardinalsSpreadThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

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Injuries & who's out

Injuries & availability

St. Louis Cardinals

  • Hunter Dobbins SPOut
  • Richard Fitts SPDay-to-day
  • Max Rajcic RPOut

Houston Astros

  • Enyel De Los Santos RPOut
  • Cristian Javier SPOut
  • Brice Matthews CFOut
  • Daulton Varsho CFOut
  • Mike Burrows SPOut
  • Jake Meyers CFOut
  • Carlos Correa SSOut
  • Brandon Walter SPOut
Availability updated Oct 2, 9:43PM UTC · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For St. Louis Cardinals vs Houston Astros: Ballpark wind and temperature can swing the run total, though the live per-park feed isn't wired into this page yet, and 11 players are listed out or questionable across both sides.
FactorThis fixture
Ballpark weatherWind and temperature at the park move run totals, but our ballpark weather module is pending a file-to-table persistence job.
Availability11 listed out or questionable (see Who's out above)

General rule: wind blowing out and warm air help the ball carry (more runs and home runs), while wind in and cold air suppress scoring; the starting pitchers listed above are the single biggest driver of the run total.

Ballpark weather module pending a file-to-table persistence job (owner). We won't show a wind/temperature number until it's persisted to the database.

Pro — weather & injury-adjusted view

See the weather- and injury-adjusted projected line and the model's with/without delta for this fixture. 🔒 Unlock with Pro

Betting angles

Markets & form
MoneylineHouston AstrosNo line posted
3-2L5 record
L5 RF7.4L5 RA3.8Home L51-4vs St. Louis Cardinals L53-2

Houston Astros moneyline form: last five 3-2, 7.4 runs/gm.

Run LineHouston Astros run lineNo line posted
3-2L5 record
L5 RF7.4L5 RA3.8Home L51-4vs St. Louis Cardinals L53-2

Houston Astros spread form: last five 3-2, 7.4 runs/gm.

Total RunsGame total · Houston Astros vs St. Louis CardinalsNo line posted

Houston Astros total runs form: last five 3-2, 7.4 runs/gm.

Team Total RunsHouston Astros team totalNo line posted
5.3runs we expect
L5 RF7.4L5 RA3.8Home L51-4vs St. Louis Cardinals L53-2

Houston Astros team total runs form: last five 3-2, 7.4 runs/gm.

St. Louis Cardinals @ Houston Astros — what the model found

Our model graded 13 betting markets for St. Louis Cardinals at Houston Astros — 13 on the game itself and 0 on individual players. One pick is free on this page.

13
Game markets graded

The model checked every betting market for this game and graded 13 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 12 graded calls for this game — with how much to bet on each — are for members.
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St. Louis Cardinals vs Houston Astros — recent results

Houston Astros have won 2 of their last 5 games; St. Louis Cardinals have won 1 of their last 5.

Houston Astros — last 5
ResultScoreOpponentWhere
L3–7CHWHome
L3–6CHWHome
W13–2ATHAway
W9–0ATHAway
L5–6ATHAway
St. Louis Cardinals — last 5
ResultScoreOpponentWhere
L4–6MILAway
L2–3MILAway
L4–8MILAway
L1–2PITAway
W5–1PITAway

St. Louis Cardinals vs Houston Astros — recent meetings

These two have met 9 times recently: Houston Astros won 1, St. Louis Cardinals won 8.

DateHouston AstrosSt. Louis CardinalsWinner
Apr 1957St. Louis Cardinals
Apr 1857St. Louis Cardinals
Apr 1849St. Louis Cardinals
Mar 2223St. Louis Cardinals
Mar 1814St. Louis Cardinals
Mar 1345St. Louis Cardinals
Mar 9103Houston Astros
Feb 2649St. Louis Cardinals
Feb 2256St. Louis Cardinals

Who’s out or in doubt

11 players are listed as out or in doubt for this game.

Houston Astros
PlayerStatus
Enyel De Los Santos RPOUT
Cristian Javier SPOUT
Brice Matthews CFOUT
Daulton Varsho CFOUT
Mike Burrows SPOUT
Jake Meyers CFOUT
Carlos Correa SSOUT
Brandon Walter SPOUT
St. Louis Cardinals
PlayerStatus
Hunter Dobbins SPOUT
Richard Fitts SPDAY-TO-DAY
Max Rajcic RPOUT

The full availability report — with what each missing player means for the bets — is further down this page.

St. Louis Cardinals @ Houston Astros — model preview

Expert analysis and top MLB betting picks for Houston Astros vs St. Louis Cardinals. Includes analysis on key players like NA. Discover MLB predictions, MLB game picks, baseball betting preview, Houston Astros vs St. Louis Cardinals stats and odds.

Houston Astros vs St. Louis Cardinals : St. Louis Cardinals +1 (-122)

Odds available at NA at time of publishing

As the Cardinals roll into Houston, they’re riding a wave of momentum that could catch even the most seasoned opponents off guard. Over the last stretch, St. Louis has showcased a potent offense, averaging 5.6 runs per game while their bats have come alive against right-handers—exactly the type of pitching they’ll face today. Meanwhile, the Astros have been vulnerable at home, struggling to keep opposing teams at bay, especially when the stakes are high. On the mound, the Cardinals’ starter has been a revelation, boasting a solid strikeout rate that could stymie Houston’s lineup. Coupled with their recent success on the road, where they've taken crucial games against tough competition, the Cardinals seem poised to not only cover the run line but potentially seize a victory outright. Taking St. Louis with a one-run cushion feels like a smart play, given the stakes and their current form.

🔒 The other 5 write-ups for this game — with how much to bet on each — are Pro.
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About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for St. Louis Cardinals vs Houston Astros in the MLB. You may also see this matchup written as Cardinals vs Astros, or as Astros vs Cardinals. The most recent game between them was Sunday 19 April 2026 at Minute Maid Park. The model has generated 13 game picks for this matchup. Review the picks and historical data above to guide your MLB betting strategy for this matchup.

St. Louis Cardinals vs Houston Astros head-to-head record

Final scores · 36 meetings on record
Houston Astros 18–16 across the last 36 meetings · 2 draws · these games average 9.6 runs (meetings on record since 2023)

Last meeting: Sun 19 Apr 2026, St. Louis Cardinals at Houston Astros: the Cardinals won 7-5.

DateGameScoreWinner
19 Apr 2026St. Louis Cardinals @ Houston Astros5–7St. Louis Cardinals
18 Apr 2026St. Louis Cardinals @ Houston Astros4–9St. Louis Cardinals
17 Apr 2026St. Louis Cardinals @ Houston Astros4–9St. Louis Cardinals
22 Mar 2026St. Louis Cardinals @ Houston Astros2–3St. Louis Cardinals
18 Mar 2026Houston Astros @ St. Louis Cardinals4–1St. Louis Cardinals
13 Mar 2026Houston Astros @ St. Louis Cardinals5–4St. Louis Cardinals
9 Mar 2026St. Louis Cardinals @ Houston Astros10–3Houston Astros
26 Feb 2026Houston Astros @ St. Louis Cardinals9–4St. Louis Cardinals
22 Feb 2026St. Louis Cardinals @ Houston Astros5–6St. Louis Cardinals
16 Apr 2025Houston Astros @ St. Louis Cardinals4–1St. Louis Cardinals

Table shows the last 10 — the record above counts all 36 meetings on file.

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