Arizona Diamondbacks vs Chicago Cubs Prediction and Picks, August 24, 2026

Both teams have been pretty even lately, each winning four of their last ten games. The Chicago Cubs have a slight advantage when facing left-handed pitchers, hitting a bit better than the Arizona Diamondbacks this year. The Cubs have also outscored their opponents by an average of 0.7 runs in their last 12 games, while the Diamondbacks have been just 0.3 runs ahead. This matchup is rated close to a coin flip, which means it could go either way. The most concrete risk here is that both teams are in similar forms, so it might be a nail-biter. Still, given the Cubs' stronger hitting against lefties and their recent performance, they look like a solid pick to win this game.

Arizona Diamondbacks vs Chicago Cubs: Over 9 Total Runs (-110)

This could lead to plenty of scoring opportunities at Chase Field, where the conditions are usually good for hitting. The Diamondbacks have averaged 0.3 more runs than their opponents in the last 12 games, while the Cubs have been slightly better at 0.7 runs ahead. With both teams showing solid offensive form, the total runs could easily reach 10 or more. However, it's worth noting that both teams have only won four of their last ten games, meaning they might struggle at times. Still, this matchup looks promising for a bet on over 9 total runs.

Arizona Diamondbacks vs Chicago Cubs: Chicago Cubs -1.5 (+114)

Arizona Diamondbacks play Chicago Cubs in the MLB. The bet we are looking at is Arizona Diamondbacks vs Chicago Cubs: Chicago Cubs -1.5 (+114). That is a alternate spreads bet. It was priced at +114 when we wrote this, so a $10 bet returns $21.40 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Arizona Diamondbacks vs Chicago Cubs: Ildemaro Vargas Under 0.5 Batter - Singles (-108)

For this bet to win, Ildemaro Vargas needs to not get a single hit tonight. This could happen because he's been struggling lately, averaging zero hits in his last three games. The Diamondbacks are up against the Cubs, who have been decent, but Vargas is facing a pitcher who gives up fewer runs than average, making it tougher for him to find a hit. Both teams have been even lately, winning four out of ten games. The Cubs have a strong average against left-handed pitchers but Vargas doesn't have a big track record. With the way he's been hitting, it's a real possibility he could end the game without a hit.

Arizona Diamondbacks vs Chicago Cubs: Pete Crow-Armstrong Under 0.5 Batter - Runs Scored (+108)

In a game at Chase Field, the Arizona Diamondbacks face off against the Chicago Cubs. Both teams have won about half of their recent games, but Pete Crow-Armstrong has been averaging just one hit per game lately. Against left-handed pitchers, the Cubs have done well, but Crow-Armstrong isn't hitting as often as he needs to for this bet to land. The Diamondbacks have shown they can score more runs than usual recently, but Crow-Armstrong is still getting hits at a lower rate than you'd want. With the risk of him not crossing home plate at all in this matchup, betting on him to score under 0.5 runs could be a smart play.

Arizona Diamondbacks vs Chicago Cubs: Gabriel Moreno Under 1.5 Batter - Hits + Runs + RBIs (-112)

Gabriel Moreno is sitting at odds of -112 for under 1.5 hits, runs, and RBIs, which looks like a decent pick in this matchup. Both the Arizona Diamondbacks and Chicago Cubs have had a tough time lately, winning only 4 out of their last 10 games. Moreno's been hitting well, but the numbers suggest this game could be tight, especially since each team has been scoring around the same amount lately. While he has been getting hits more often lately, that could easily change against a solid Cubs lineup. Betting on under 1.5 gives us a shot at a favorable outcome, but it's close, and there's a real chance he could break through and surprise us.

That is the whole read on this one. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.