On October 11, 2026 our model has run Detroit Lions at Arizona Cardinals and priced every market it can. Our strongest call is Arizona Cardinals To Win (+185), which we rate long shot confidence. Every bet below is our own number against the price on the board, in plain English.
Every bet we like in this game
Arizona Cardinals vs Detroit Lions: Arizona Cardinals To Win (+185)
Odds correct at time of publishing
The Arizona Cardinals need to beat the Detroit Lions tonight for this bet to win. The Cardinals have shown they can score, moving the chains over 18 times a game last season. Even though their defense allowed a lot of yards, they have home advantage, which often helps teams play better.
The Lions are solid, but they can be vulnerable on the road. Arizona is a bit of an underdog, but they have a real chance to pull off the win. The biggest risk is that both teams are closely matched, so it could go either way. Still, with the right performance, the Cardinals could take this one.
Arizona Cardinals vs Detroit Lions: Under 54.5 Total Points (-110)
Odds correct at time of publishing
For this game, we need the total points scored by both teams to be under 54.5. The Arizona Cardinals and Detroit Lions both have solid defenses that have been pretty effective at limiting yards. Last season, the Cardinals gave up around 370 yards a game, while the Lions were slightly better, allowing about 351 yards. This matchup suggests that scoring might be tougher than expected.
Both teams also struggle to move the ball consistently, with the Cardinals averaging about 18 first downs a game and the Lions a bit better at 19. With those numbers, our figures estimate a combined score closer to 46.8, which is well below the mark we need. The biggest worry is that both teams can surprise us with big plays, but overall, it looks promising for an under bet.
Arizona Cardinals vs Detroit Lions: Arizona Cardinals +4.5 Point Spread (-108)
Odds correct at time of publishing
For the Cardinals to cover the spread tonight, they need to keep the game within 4.5 points against the Lions. The Cardinals have been moving the chains pretty well, averaging over 18 first downs a game last season. That means they can put together some solid drives and put pressure on Detroit's defense, which has given up a decent number of yards.
The Lions have also allowed a fair amount of yards, so it's likely this will be a close matchup. One risk to watch is that both teams are pretty evenly matched based on past performances, which makes it hard to predict.
Arizona Cardinals vs Detroit Lions: Trey McBride Yes Anytime Touchdown Scorer (+130)
Odds correct at time of publishing
Trey McBride has been a solid option for the Arizona Cardinals lately, making him a good choice for a touchdown in this game. The Cardinals often struggle on defense, giving up a lot of yards, which could lead to scoring chances for McBride. Plus, they've had decent success moving the ball, allowing him to get in the end zone.
The Lions are tough, too, but McBride has shown he can find space against defenses like Detroit's. The risk is that both teams are pretty close in skill, so it might turn out differently than expected. Still, with McBride's current form, this bet looks promising.
That is the whole read on this one. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.