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Model picks & player props
NFL
San Francisco
Sun 20 Sep 2026, 4:25 PM ET
Miami Dolphins
VS
San Francisco 49ers

Miami Dolphins vs San Francisco 49ers Prediction & Picks

Our model graded 51 markets for Miami Dolphins vs San Francisco 49ers and backs Miami Dolphins 4.5 hardest, a lean, and $100 on it returns about $248.

20
Game markets graded
31
Props graded
The model's one call for this gamethe prediction, first Free
Miami Dolphins 4.5
Miami Dolphins 4.5 Alternate Spreads H1
You bet$10 If it wins$24.80Best price+148
Our confidenceLean
Chance to win46.0%
The price says38.0%

The model graded 51 markets for Miami Dolphins vs San Francisco 49ers (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $248 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 20 Sep 2026, 4:25 PM ET at San Francisco.

This game's bets

The rest of this game's boardgraded market by market
Alternate Spreads H1 Miami Dolphins 4.5 Lean46% chance +148
Team Totals H2 Members only Lean54% chance Members
Moneyline Q1 Members only Long-shot34% chance Members
Moneyline 3 Way H1 Members only Long-shot26% chance Members
Moneyline H1 Members only Long-shot28% chance Members
Alternate Spreads H1 Members only High66% chance Members
Alternate Spreads Q1 Members only Lean50% chance Members
Alternate Team Total Points Members only Long-shot34% chance Members
Alternate Team Totals H1 Members only Lean53% chance Members
Receptions (Alt) × 1 prop Leanup to 41% Members
Receptions × 2 props Highup to 75% Members
Interceptions Thrown × 1 prop Highup to 80% Members
Last Touchdown Scorer × 12 props Long-shotup to 28% Members
Receiving Yards × 2 props Highup to 68% Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

Miami Dolphins and San Francisco 49ers last met on Sun 20 Sep 2026: San Francisco 49ers won 35-13. Their next game gets a fresh preview here the moment it is priced. Today's board: every NFL game priced right now.

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Game picks

GOOD PRICE in green
Alternate Spreads H1
Miami Dolphins
4.5
+148
+ 19 more markets
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All 20 game markets and 31 player props for this matchup — every line, every call the model backs — plus every pick across the slate. Join 66,636+ members.

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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
OverTeam Totals H2The model likes this price 🔒 Unlock with Pro
Miami DolphinsMoneyline Q1The model likes this price 🔒 Unlock with Pro
Miami DolphinsMoneyline 3 Way H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsMoneyline H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads Q1The model likes this price 🔒 Unlock with Pro
UnderAlternate Team Total PointsThe model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
UnderAlternate Team Total PointsThe model likes this price 🔒 Unlock with Pro
OverAlternate Team Totals H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsSpreads H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsMoneyline Q3The model likes this price 🔒 Unlock with Pro
UnderAlternate Team Total PointsThe model likes this price 🔒 Unlock with Pro
OverAlternate Team Total PointsThe model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro
OverAlternate Team Total PointsThe model likes this price 🔒 Unlock with Pro
Miami DolphinsAlternate Spreads H1The model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

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Injuries & who's out

Injuries & availability

Miami Dolphins

  • Dante Trader Jr. SQuestionable
  • Storm Duck CBOut
  • Justin Joly TEQuestionable
  • Jaylen Wright RBQuestionable
  • Caleb Douglas WRQuestionable
  • Kenneth Grant DTOut
  • Chris Bell WRQuestionable
  • Austin Jackson OTQuestionable
  • JuJu Brents CBQuestionable
  • Tucker Addington LSQuestionable
  • Robert Beal Jr. DEQuestionable
  • Reese Taylor CBOut
  • Jackson Woodard LBQuestionable

San Francisco 49ers

  • Mike Evans WRQuestionable
  • Marques Sigle SOut
  • Upton Stout CBQuestionable
  • Kyle Juszczyk FBOut
  • James Thompson Jr. DTDoubtful
  • Nick Bosa DEDoubtful
  • Christian Kirk WROut
Availability updated Oct 8, 11:58PM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Miami Dolphins vs San Francisco 49ers: Weather isn't a tracked factor for this fixture, and 20 players are listed out or questionable across both sides.
FactorThis fixture
Availability20 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

Pro — weather & injury-adjusted view

See the weather- and injury-adjusted projected line and the model's with/without delta for this fixture. 🔒 Unlock with Pro

Player props

GOOD PRICE in green
PlayerTeamStat
Mike Evans SF Receptions (Alt)
Mike Evans SF Receptions
Brock Purdy SF Interceptions Thrown
Brock Purdy SF Last Touchdown Scorer
Mike Evans SF Receiving Yards

+ 31 player props graded for this game — the line, the call and how much to put on each, with Pro.

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Betting angles

Markets & form
MoneylineMiami Dolphins to winNo line posted

Miami Dolphins vs San Francisco 49ers moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadMiami Dolphins spreadNo line posted

Miami Dolphins vs San Francisco 49ers spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total PointsDolphins @ 49ersNo line posted

San Francisco 49ers vs Miami Dolphins game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Miami Dolphins @ San Francisco 49ers — what the model found

Our model graded 51 betting markets for Miami Dolphins at San Francisco 49ers — 20 on the game itself and 31 on individual players. One pick is free on this page.

20
Game markets graded
31
Player bets graded

The model checked every betting market for this game and graded 51 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 50 graded calls for this game — with how much to bet on each — are for members.
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Miami Dolphins vs San Francisco 49ers — recent results

San Francisco 49ers have won 5 of their last 5 games; Miami Dolphins have won 0 of their last 5.

San Francisco 49ers — last 5
ResultScoreOpponentWhere
W24–14DENHome
W36–30ARIHome
W35–13MIAHome
W27–7LARAway
W18–12LVAway
Miami Dolphins — last 5
ResultScoreOpponentWhere
L10–15MINAway
L10–24KCHome
L13–35SFAway
L13–27LVAway
L12–17ATLHome

Miami Dolphins vs San Francisco 49ers — recent meetings

These two have met 1 time recently: San Francisco 49ers won 1, Miami Dolphins won 0.

DateSan Francisco 49ersMiami DolphinsWinner
Sep 203513San Francisco 49ers

Who’s out or in doubt

20 players are listed as out or in doubt for this game.

San Francisco 49ers
PlayerStatus
Mike Evans WRQUESTIONABLE
Marques Sigle SOUT
Upton Stout CBQUESTIONABLE
Kyle Juszczyk FBOUT
James Thompson Jr. DTDOUBTFUL
Nick Bosa DEDOUBTFUL
Christian Kirk WROUT
Miami Dolphins
PlayerStatus
Dante Trader Jr. SQUESTIONABLE
Storm Duck CBOUT
Justin Joly TEQUESTIONABLE
Jaylen Wright RBQUESTIONABLE
Caleb Douglas WRQUESTIONABLE
Kenneth Grant DTOUT
Chris Bell WRQUESTIONABLE
Austin Jackson OTQUESTIONABLE

The full availability report — with what each missing player means for the bets — is further down this page.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Miami Dolphins vs San Francisco 49ers in the NFL. You may also see this matchup written as Dolphins vs 49ers, or as 49ers vs Dolphins. The most recent game between them was Sunday 20 September 2026 at San Francisco. The model has generated 20 game picks and 31 player props for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Miami Dolphins vs San Francisco 49ers head-to-head record

Final scores · 5 meetings on record
Miami Dolphins 3–2 across the last 5 meetings · these games average 51.8 points (meetings on record since 2016)

Last meeting: Sun 20 Sep 2026, Miami Dolphins at San Francisco 49ers: the 49ers won 35-13.

DateGameScoreWinner
20 Sep 2026Miami Dolphins @ San Francisco 49ers35–13San Francisco 49ers
22 Dec 2024San Francisco 49ers @ Miami Dolphins29–17Miami Dolphins
4 Dec 2022Miami Dolphins @ San Francisco 49ers33–17San Francisco 49ers
11 Oct 2020Miami Dolphins @ San Francisco 49ers17–43Miami Dolphins
27 Nov 2016San Francisco 49ers @ Miami Dolphins31–24Miami Dolphins

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