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Odds and preview
NFL
Sun 15 Nov 2026, 4:25PM ET
San Francisco 49ers
6-1 · 2-1 awayWWWWL
VS
Dallas Cowboys
3-5 · 1-3 at homeWLLWL

San Francisco 49ers vs Dallas Cowboys prediction and odds · Sun 15 Nov

Dallas Cowboys host San Francisco 49ers on Sunday 15 November.

Sunday 15 November 2026: San Francisco 49ers at Dallas Cowboys

Dallas Cowboys host San Francisco 49ers on Sunday 15 November. The bookies' prices make the 49ers about a 7 in 10 chance to win. Our model's pick lands about 5 days before kickoff.
How they've been scoring this season
San Francisco 49ersDallas Cowboys
Won-lost6-13-5
Points scored per game28.127.4
Points allowed per game19.926.6
On the road / at home2-1 away1-3 at home
Last 5 gamesWWWWLWLLWL
Their games average 51.0 total points this season.
From the 7 San Francisco 49ers and 8 Dallas Cowboys games on our books this season.

San Francisco 49ers vs Dallas Cowboys odds

Prices for this game

Best price: Cowboys pay $2.76, 49ers pay $1.51 (the best of 7 bookies we checked). $100 on the 49ers returns $151.

Fair chance (our read of the prices, with the bookies' cut taken out): Cowboys about 3 in 10, 49ers about 7 in 10.

How much the bookies keep: about $4.21 of every $100 bet on this game.

Since betting opened: the price has barely moved.

Our pick for this game

Our model's pick lands about 5 days before kickoff. Today's NFL picks are already up: see today's NFL picks.

Injuries & who's out

Injuries & availability

San Francisco 49ers

  • De'Zhaun Stribling WROut
  • Brandon Aiyuk WROut
  • Marques Sigle SQuestionable
  • Garret Wallow LBQuestionable
  • Luke Gifford LBQuestionable
  • Upton Stout CBQuestionable
  • Nick Bosa DEQuestionable
  • Deebo Samuel Sr. WRQuestionable
  • Demarcus Robinson WROut
  • Mike Evans WRQuestionable
  • Christian McCaffrey RBQuestionable

Dallas Cowboys

  • Dee Winters LBQuestionable
  • Luke Schoonmaker TEQuestionable
  • KaVontae Turpin WRQuestionable
  • P.J. Locke SQuestionable
  • Caleb Downs SQuestionable
  • Malachi Lawrence LBQuestionable
  • Jake Ferguson TEQuestionable
  • Jonathan Bullard DTOut
  • Marist Liufau LBOut
Availability updated Nov 4, 2:19AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

San Francisco 49ers vs Dallas Cowboys: game facts

When it starts and how they have been going

San Francisco 49ers play Dallas Cowboys on Sunday 15 November 2026. Kick-off is 4:25 PM ET. It is an NFL game.

San Francisco 49ers: last 5 results

  1. 25 Oct 2026Lostat Atlanta Falcons 20-29
  2. 19 Oct 2026Wonvs Washington Commanders 23-17
  3. 11 Oct 2026Wonat Seattle Seahawks 32-29
  4. 4 Oct 2026Wonvs Denver Broncos 24-14
  5. 27 Sep 2026Wonvs Arizona Cardinals 36-30

Dallas Cowboys: last 5 results

  1. 1 Nov 2026Lostvs Arizona Cardinals 30-33
  2. 26 Oct 2026Wonat Philadelphia Eagles 38-21
  3. 18 Oct 2026Lostat Green Bay Packers 13-23
  4. 8 Oct 2026Lostvs Tampa Bay Buccaneers 16-24
  5. 4 Oct 2026Wonat Houston Texans 34-30

Quick answers

When is San Francisco 49ers vs Dallas Cowboys? San Francisco 49ers vs Dallas Cowboys is on Sunday 15 November 2026. Kick-off is 4:25 PM ET.

How have San Francisco 49ers and Dallas Cowboys done lately? San Francisco 49ers won 4 and lost 1 of the last 5 results we hold. Dallas Cowboys won 2 and lost 3 of the last 5 results we hold.

From the final scores we hold. Newest game first.

San Francisco 49ers vs Dallas Cowboys head-to-head record

Final scores · 7 meetings on record
San Francisco 49ers 4–3 across the last 7 meetings · these games average 48.9 points (meetings on record since 2016)

Last meeting: Sun 27 Oct 2024, Dallas Cowboys at San Francisco 49ers: the 49ers won 30-24.

DateGameScoreWinner
27 Oct 2024Dallas Cowboys @ San Francisco 49ers30–24San Francisco 49ers
8 Oct 2023Dallas Cowboys @ San Francisco 49ers42–10San Francisco 49ers
22 Jan 2023Dallas Cowboys @ San Francisco 49ers19–12San Francisco 49ers
16 Jan 2022San Francisco 49ers @ Dallas Cowboys17–23San Francisco 49ers
20 Dec 2020San Francisco 49ers @ Dallas Cowboys41–33Dallas Cowboys
22 Oct 2017Dallas Cowboys @ San Francisco 49ers10–40Dallas Cowboys
2 Oct 2016Dallas Cowboys @ San Francisco 49ers17–24Dallas Cowboys
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