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Model picks & player props
NFL
Philadelphia
Sun 11 Jan 2026, 4:30 PM ET
San Francisco 49ers
VS
Philadelphia Eagles

San Francisco 49ers vs Philadelphia Eagles Prediction & Picks

Our model graded 2 markets for San Francisco 49ers vs Philadelphia Eagles and backs San Francisco 49ers hardest, a lean, and $100 on it returns about $315.

2
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first Free
San Francisco 49ers
to win
San Francisco 49ers Moneyline
You bet$10 If it wins$31.50Best price+215
Our confidenceLean
Chance to win51.5%
The price says31.8%

The model graded 2 markets for San Francisco 49ers vs Philadelphia Eagles (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $315 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 11 Jan 2026, 4:30 PM ET at Philadelphia.

This game's bets

The rest of this game's boardgraded market by market
Moneyline San Francisco 49ers Lean51% chance +215
Spread Members only Lean53% chance Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

San Francisco 49ers and Philadelphia Eagles last met on Sun 11 Jan 2026: San Francisco 49ers won 23-19. Their next game gets a fresh preview here the moment it is priced. Today's board: every NFL game priced right now.

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Game picks

GOOD PRICE in green
Moneyline
San Francisco 49ers
+215
+ 1 more market
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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
San Francisco 49ersMoneylineThe model likes this price 🔒 Unlock with Pro
San Francisco 49ersSpreadThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

Pro shows you, in plain English, how far each price is off — and how much to put on it. No maths needed on your side.

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Injuries & who's out

Injuries & availability

San Francisco 49ers

  • Marques Sigle SQuestionable
  • Garret Wallow LBQuestionable
  • Luke Gifford LBQuestionable
  • Upton Stout CBQuestionable
  • Nick Bosa DEQuestionable
  • Deebo Samuel Sr. WRQuestionable
  • Demarcus Robinson WROut
  • De'Zhaun Stribling WROut
  • Mike Evans WRQuestionable
  • Christian McCaffrey RBQuestionable

Philadelphia Eagles

  • Jakorian Bennett CBOut
  • Jihaad Campbell LBOut
  • Britain Covey WROut
  • Dontayvion Wicks WROut
  • DeVonta Smith WROut
  • Jonathan Jones CBOut
  • Dameon Pierce RBOut
Availability updated Nov 1, 3:12AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For San Francisco 49ers vs Philadelphia Eagles: Weather isn't a tracked factor for this fixture, and 17 players are listed out or questionable across both sides.
FactorThis fixture
Availability17 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

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Betting angles

Markets & form
MoneylineSan Francisco 49ers to winNo line posted

San Francisco 49ers vs Philadelphia Eagles moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadSan Francisco 49ers spreadNo line posted

San Francisco 49ers vs Philadelphia Eagles spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total Points49ers @ EaglesNo line posted

Philadelphia Eagles vs San Francisco 49ers game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

San Francisco 49ers @ Philadelphia Eagles — what the model found

Our model graded 2 betting markets for San Francisco 49ers at Philadelphia Eagles — 2 on the game itself and 0 on individual players. One pick is free on this page.

2
Game markets graded

The model checked every betting market for this game and graded 2 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 1 graded call for this game — with how much to bet on each — are for members.
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San Francisco 49ers vs Philadelphia Eagles — recent results

Philadelphia Eagles have won 0 of their last 5 games; San Francisco 49ers have won 4 of their last 5.

Philadelphia Eagles — last 5
ResultScoreOpponentWhere
L21–38DALHome
L14–25CARHome
L17–19JAXAway
L20–24LARHome
L7–27CHIAway
San Francisco 49ers — last 5
ResultScoreOpponentWhere
L20–29ATLAway
W23–17WSHHome
W32–29SEAAway
W24–14DENHome
W36–30ARIHome

San Francisco 49ers vs Philadelphia Eagles — recent meetings

These two have met 1 time recently: Philadelphia Eagles won 0, San Francisco 49ers won 1.

DatePhiladelphia EaglesSan Francisco 49ersWinner
Jan 111923San Francisco 49ers

Who’s out or in doubt

17 players are listed as out or in doubt for this game.

Philadelphia Eagles
PlayerStatus
Jakorian Bennett CBOUT
Jihaad Campbell LBOUT
Britain Covey WROUT
Dontayvion Wicks WROUT
DeVonta Smith WROUT
Jonathan Jones CBOUT
Dameon Pierce RBOUT
San Francisco 49ers
PlayerStatus
Marques Sigle SQUESTIONABLE
Garret Wallow LBQUESTIONABLE
Luke Gifford LBQUESTIONABLE
Upton Stout CBQUESTIONABLE
Nick Bosa DEQUESTIONABLE
Deebo Samuel Sr. WRQUESTIONABLE
Demarcus Robinson WROUT
De'Zhaun Stribling WROUT

The full availability report — with what each missing player means for the bets — is further down this page.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for San Francisco 49ers vs Philadelphia Eagles in the NFL. You may also see this matchup written as 49ers vs Eagles, or as Eagles vs 49ers. The most recent game between them was Sunday 11 January 2026 at Philadelphia. The model has generated 2 game picks for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

San Francisco 49ers vs Philadelphia Eagles: game facts

Past meetings and recent results

Where they last met

  • 11 Jan 2026San Francisco 49ers beat Philadelphia Eagles 23-19 on the road

San Francisco 49ers: last 5 results

  1. 25 Oct 2026Lostat Atlanta Falcons 20-29
  2. 19 Oct 2026Wonvs Washington Commanders 23-17
  3. 11 Oct 2026Wonat Seattle Seahawks 32-29
  4. 4 Oct 2026Wonvs Denver Broncos 24-14
  5. 27 Sep 2026Wonvs Arizona Cardinals 36-30

Philadelphia Eagles: last 5 results

  1. 26 Oct 2026Lostvs Dallas Cowboys 21-38
  2. 18 Oct 2026Lostvs Carolina Panthers 14-25
  3. 11 Oct 2026Lostat Jacksonville Jaguars 17-19
  4. 4 Oct 2026Lostvs Los Angeles Rams 20-24
  5. 28 Sep 2026Lostat Chicago Bears 7-27

Quick answers

Who won the last Philadelphia Eagles vs San Francisco 49ers game? San Francisco 49ers won their last meeting 23-19 on 11 January 2026.

How have San Francisco 49ers and Philadelphia Eagles done lately? San Francisco 49ers won 4 and lost 1 of the last 5 results we hold. Philadelphia Eagles won 0 and lost 5 of the last 5 results we hold.

From the final scores we hold. Newest game first.

San Francisco 49ers vs Philadelphia Eagles head-to-head record

Final scores · 6 meetings on record
Even at 3–3 across the last 6 meetings · these games average 42.8 points (meetings on record since 2017)

Last meeting: Sun 11 Jan 2026, San Francisco 49ers at Philadelphia Eagles: the 49ers won 23-19.

DateGameScoreWinner
11 Jan 2026San Francisco 49ers @ Philadelphia Eagles19–23San Francisco 49ers
3 Dec 2023San Francisco 49ers @ Philadelphia Eagles19–42San Francisco 49ers
29 Jan 2023San Francisco 49ers @ Philadelphia Eagles31–7Philadelphia Eagles
19 Sep 2021San Francisco 49ers @ Philadelphia Eagles11–17San Francisco 49ers
4 Oct 2020Philadelphia Eagles @ San Francisco 49ers20–25Philadelphia Eagles
29 Oct 2017San Francisco 49ers @ Philadelphia Eagles33–10Philadelphia Eagles

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