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Model picks & player props
San Francisco 49ers
VS
Philadelphia Eagles

San Francisco 49ers vs Philadelphia Eagles Picks & Predictions

Model updated Sep 22, 7:43AM UTC

Our model graded 2 markets for San Francisco 49ers vs Philadelphia Eagles and backs San Francisco 49ers hardest, a lean, and $100 on it returns about $315.

NFL
Philadelphia
Sun 11 Jan 2026, 9:30PM
2
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first
San Francisco 49ers Moneyline +215

The model graded 2 markets for San Francisco 49ers vs Philadelphia Eagles (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $315 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 11 Jan 2026, 9:30PM at Philadelphia.

Our confidenceLean
Chance to win51.5%
The price says31.8%
Best price+215
The rest of this game's boardgraded market by market
Moneyline San Francisco 49ers Lean51% chance +215
Spread Members only Lean53% chance Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

San Francisco 49ers and Philadelphia Eagles last met on Sun 11 Jan 2026. What follows is the model's graded record from that game; a new preview appears here the moment the next one is priced. Today's board: every NFL game priced right now.

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This game is done — the model’s call CASHED
San Francisco 49ers · $100 returned $315

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Every pick is logged and graded — nothing hidden after the fact. See the verified record
This gameBets like this sit in our formula’s best NFL market — 349 of 542 right (nfl alternate team total points overs)
This bet type · last timeSep 22
Over 14.5
New York Giants @ Los Angeles Rams
CASHED
STAKE $100RETURNS $132
Today’s picks post before the games start.logged in public before tip-offSee the picks page

Game picks

GOOD PRICE in green
Moneyline
San Francisco 49ers
+215
+ 1 more market
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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
San Francisco 49ersMoneylineThe model likes this price 🔒 Unlock with Pro
San Francisco 49ersSpreadThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

Pro shows you, in plain English, how far each price is off — and how much to put on it. No maths needed on your side.

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Injuries & who's out

Injuries & availability

San Francisco 49ers

  • Romello Height DEQuestionable
  • James Thompson Jr. DTDoubtful
  • Demarcus Robinson WROut
  • Mike Evans WRQuestionable
  • Brandon Aiyuk WROut
  • Jack Jones CBQuestionable
  • De'Zhaun Stribling WROut
  • Jake Tonges TEOut

Philadelphia Eagles

  • Dallas Goedert TEDoubtful
  • Jonathan Greenard LBOut
  • Saquon Barkley RBQuestionable
  • Landon Dickerson GOut
  • Eli Stowers TEOut
Availability updated Sep 22, 4:14AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For San Francisco 49ers vs Philadelphia Eagles: Weather isn't a tracked factor for this fixture, and 13 players are listed out or questionable across both sides.
FactorThis fixture
Availability13 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

Pro — weather & injury-adjusted view

See the weather- and injury-adjusted projected line and the model's with/without delta for this fixture. 🔒 Unlock with Pro

Betting angles

Markets & form
MoneylineSan Francisco 49ers to winNo line posted

San Francisco 49ers vs Philadelphia Eagles moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadSan Francisco 49ers spreadNo line posted

San Francisco 49ers vs Philadelphia Eagles spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total Points49ers @ EaglesNo line posted

Philadelphia Eagles vs San Francisco 49ers game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

San Francisco 49ers @ Philadelphia Eagles — what the model found

Our model graded 2 betting markets for San Francisco 49ers at Philadelphia Eagles — 2 on the game itself and 0 on individual players. One pick is free on this page.

2
Game markets graded

The model checked every betting market for this game and graded 2 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 1 graded call for this game — with how much to bet on each — are for members.
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San Francisco 49ers vs Philadelphia Eagles — recent results

Philadelphia Eagles have won 2 of their last 5 games; San Francisco 49ers have won 4 of their last 5.

Philadelphia Eagles — last 5
ResultScoreOpponentWhere
W24–20TENAway
W24–22WSHHome
L13–30CINHome
L21–24NEAway
L7–24BALAway
San Francisco 49ers — last 5
ResultScoreOpponentWhere
W35–13MIAHome
W27–7LARAway
W18–12LVAway
W41–17LACAway
L13–19TENHome

San Francisco 49ers vs Philadelphia Eagles — recent meetings

These two have met 1 time recently: Philadelphia Eagles won 0, San Francisco 49ers won 1.

DatePhiladelphia EaglesSan Francisco 49ersWinner
Jan 111923San Francisco 49ers

Who’s out or in doubt

13 players are listed as out or in doubt for this game.

Philadelphia Eagles
PlayerStatus
Dallas Goedert TEDOUBTFUL
Jonathan Greenard LBOUT
Saquon Barkley RBQUESTIONABLE
Landon Dickerson GOUT
Eli Stowers TEOUT
San Francisco 49ers
PlayerStatus
Romello Height DEQUESTIONABLE
James Thompson Jr. DTDOUBTFUL
Demarcus Robinson WROUT
Mike Evans WRQUESTIONABLE
Brandon Aiyuk WROUT
Jack Jones CBQUESTIONABLE
De'Zhaun Stribling WROUT
Jake Tonges TEOUT

The full availability report — with what each missing player means for the bets — is further down this page.

Track record for this matchup

Logged & graded
2
Total Picks
—
Hit Rate

Hit rate is how often the pick landed — not profit; favourites can win often and still lose money.

DateMarketPickResult
11 Jan 26 Spread San Francisco 49ers +5.5 ✓ HIT
11 Jan 26 Moneyline San Francisco 49ers ✓ HIT

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for San Francisco 49ers vs Philadelphia Eagles in the NFL. You may also see this matchup written as 49ers vs Eagles, or as Eagles vs 49ers. The most recent game between them was Sunday 11 January 2026 at Philadelphia. The model has generated 2 game picks for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Head-to-head record

Final scores · 6 meetings on record
Even at 3–3 across the last 6 meetings · these games average 42.8 points (meetings on record since 2017)
DateGameScoreWinner
11 Jan 2026San Francisco 49ers @ Philadelphia Eagles19–23San Francisco 49ers
3 Dec 2023San Francisco 49ers @ Philadelphia Eagles19–42San Francisco 49ers
29 Jan 2023San Francisco 49ers @ Philadelphia Eagles31–7Philadelphia Eagles
19 Sep 2021San Francisco 49ers @ Philadelphia Eagles11–17San Francisco 49ers
4 Oct 2020Philadelphia Eagles @ San Francisco 49ers20–25Philadelphia Eagles
29 Oct 2017San Francisco 49ers @ Philadelphia Eagles33–10Philadelphia Eagles

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