Chicago White Sox vs Pittsburgh Pirates Prediction and Picks, September 9, 2026

The Chicago White Sox have been solid lately, scoring about 1.3 runs more than their opponents in the last 12 games. However, the Pittsburgh Pirates have been right on their heels, winning 6 of their last 10 games. When facing left-handed pitchers, the Pirates have struggled a bit more than the White Sox, but they still have a decent chance to compete here. The matchup is pretty close, so it feels like a good opportunity to back the Pirates at these odds. Their recent form shows they can hang with the best, and the Sox's advantage isn't huge. The biggest risk is the Pirates' weaker hitting against lefties, but with the game being so close, it's worth taking a shot on them to win.

Chicago White Sox vs Pittsburgh Pirates: Pittsburgh Pirates +1 Spread (-119)

The Chicago White Sox have been playing well recently, scoring about 1.3 runs more than their opponents in the last 12 games. They've also managed to win 5 of their last 10 games, showing good form. However, the Pittsburgh Pirates have also been strong, winning 6 of their last 10 and coming close in their games, with their recent margin only being 0.1 runs ahead. Against left-handed pitchers, the Pirates have struggled a bit more than the White Sox, hitting lower numbers this season. Still, with the odds at Pittsburgh Pirates +1, they have a solid chance to perform well. Just remember, the White Sox are at home, and that can always be a tough environment for visitors.

Chicago White Sox vs Pittsburgh Pirates: Over 7.5 Total Runs (-122)

Chicago White Sox play Pittsburgh Pirates in the MLB. The bet we are looking at is Chicago White Sox vs Pittsburgh Pirates: Over 7.5 Total Runs (-122). That is a totals bet. It was priced at -122 when we wrote this, so a $10 bet returns $18.20 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Chicago White Sox vs Pittsburgh Pirates: Colson Montgomery Under 0.5 Batter - Hits (+102)

Colson Montgomery has struggled lately, not getting any hits in his last three games. The betting pick here is to bet on him getting under half a hit against the Pittsburgh Pirates. The Chicago White Sox have been hitting well against left-handed pitchers, but Montgomery hasn't been a big part of that success lately. The White Sox are averaging 1.3 runs more than the Pirates over the last 12 games, but the Pirates are also playing well, winning six of their last ten. With Montgomery's recent slump and the pressure of facing a solid Pittsburgh lineup, there's a chance he might continue this dry spell. It's a good opportunity to consider betting on him to get under half a hit.

Chicago White Sox vs Pittsburgh Pirates: Munetaka Murakami Under 0.5 Batter - Hits (+108)

Munetaka Murakami has been solid this season, but he hasn't been hitting much at home lately. At Guaranteed Rate Field, he averages just 0.4 hits over his last ten games, which isn't great. Plus, the Pittsburgh Pirates have been strong against left-handed pitchers, while Murakami's stats show he might struggle against them. Looking at his overall performance, his batting average is decent, but it's clear that he may not find success today. With the Pirates doing better against lefties and Murakami's recent home numbers, betting on him to get less than half a hit seems like a smart move. Just keep in mind, he could surprise us, but the numbers don't favor him here.

Chicago White Sox vs Pittsburgh Pirates: Oneil Cruz Under 0.5 Batter - Hits (+116)

The odds for Oneil Cruz to get under 0.5 hits are offering good value at +116. The Chicago White Sox have been solid against left-handed pitchers this season, and Cruz has struggled lately, averaging no hits in his last three games. On top of that, the Pittsburgh Pirates are not hitting well against lefties, with an OPS that is below the league average. While Cruz is a talented player, the numbers suggest he might have a tough time today. The White Sox have been scoring well, averaging 1.3 runs more per game than the Pirates in our recent grading. With Cruz not finding success at the plate, this bet has a real chance to come through.

That is the whole read on this one. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.