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Model picks & player props
NFL
Buffalo
Sun 16 Nov 2025, 1:00 PM ET
Tampa Bay Buccaneers
VS
Buffalo Bills

Tampa Bay Buccaneers vs Buffalo Bills Prediction & Picks

Our model graded 3 markets for Tampa Bay Buccaneers vs Buffalo Bills and backs Tampa Bay Buccaneers 5.5 hardest, a lean, and $100 on it returns about $198.

3
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first Free
Tampa Bay Buccaneers
with a 5.5-point head start
Tampa Bay Buccaneers 5.5 Spread
You bet$10 If it wins$19.80Best price-102
Our confidenceLean
Chance to win58.7%
The price says50.5%

The model graded 3 markets for Tampa Bay Buccaneers vs Buffalo Bills (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $198 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 16 Nov 2025, 1:00 PM ET at Buffalo.

This game's bets

The rest of this game's boardgraded market by market
Spread Tampa Bay Buccaneers 5.5 Lean59% chance -102
Spread Members only Lean59% chance Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

Tampa Bay Buccaneers and Buffalo Bills last met on Sun 16 Nov 2025. Their next game gets a fresh preview here the moment it is priced. Today's board: every NFL game priced right now.

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Game picks

GOOD PRICE in green
Spread
Tampa Bay Buccaneers
+5.5
-102
+ 2 more markets
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All 3 game markets and 0 player props for this matchup — every line, every call the model backs — plus every pick across the slate. Join 67,095+ members.

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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

Pro shows you, in plain English, how far each price is off — and how much to put on it. No maths needed on your side.

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Injuries & who's out

Injuries & availability

Tampa Bay Buccaneers

  • Baker Mayfield QBOut
  • Antoine Winfield Jr. SOut
  • Billy Schrauth GOut
  • Benjamin Morrison CBOut
  • SirVocea Dennis LBOut
  • Luke Haggard GOut
  • DeMonte Capehart DTOut

Buffalo Bills

  • Landon Jackson DEQuestionable
  • Dee Alford CBQuestionable
  • Ed Oliver DTOut
  • DJ Moore WRQuestionable
  • Joshua Palmer WROut
  • Te'Cory Couch CBQuestionable
Availability updated Oct 11, 3:11AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Tampa Bay Buccaneers vs Buffalo Bills: Weather isn't a tracked factor for this fixture, and 13 players are listed out or questionable across both sides.
FactorThis fixture
Availability13 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

Pro — weather & injury-adjusted view

See the weather- and injury-adjusted projected line and the model's with/without delta for this fixture. 🔒 Unlock with Pro

Betting angles

Markets & form
MoneylineBuffalo Bills to winNo line posted

Buffalo Bills vs Tampa Bay Buccaneers moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadTampa Bay Buccaneers spreadNo line posted

Tampa Bay Buccaneers vs Buffalo Bills spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total PointsBuccaneers @ BillsNo line posted

Buffalo Bills vs Tampa Bay Buccaneers game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Tampa Bay Buccaneers @ Buffalo Bills — what the model found

Our model graded 3 betting markets for Tampa Bay Buccaneers at Buffalo Bills — 3 on the game itself and 0 on individual players. One pick is free on this page.

3
Game markets graded

The model checked every betting market for this game and graded 3 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 2 graded calls for this game — with how much to bet on each — are for members.
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Tampa Bay Buccaneers vs Buffalo Bills — recent results

Buffalo Bills have won 4 of their last 5 games; Tampa Bay Buccaneers have won 1 of their last 5.

Buffalo Bills — last 5
ResultScoreOpponentWhere
L26–29NEHome
W24–16LACHome
W41–31DETHome
W36–31HOUAway
W28–27PITHome
Tampa Bay Buccaneers — last 5
ResultScoreOpponentWhere
W24–16DALAway
L14–17GBHome
L16–23MINHome
L19–23CLEHome
L27–33CINAway

Who’s out or in doubt

13 players are listed as out or in doubt for this game.

Buffalo Bills
PlayerStatus
Landon Jackson DEQUESTIONABLE
Dee Alford CBQUESTIONABLE
Ed Oliver DTOUT
DJ Moore WRQUESTIONABLE
Joshua Palmer WROUT
Te'Cory Couch CBQUESTIONABLE
Tampa Bay Buccaneers
PlayerStatus
Baker Mayfield QBOUT
Antoine Winfield Jr. SOUT
Billy Schrauth GOUT
Benjamin Morrison CBOUT
SirVocea Dennis LBOUT
Luke Haggard GOUT
DeMonte Capehart DTOUT

The full availability report — with what each missing player means for the bets — is further down this page.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Tampa Bay Buccaneers vs Buffalo Bills in the NFL. You may also see this matchup written as Buccaneers vs Bills, or as Bills vs Buccaneers. The most recent game between them was Sunday 16 November 2025 at Buffalo. The model has generated 3 game picks for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Tampa Bay Buccaneers vs Buffalo Bills head-to-head record

Final scores · 4 meetings on record
Buffalo Bills 3–1 across the last 4 meetings · these games average 58.8 points (meetings on record since 2017)

Last meeting: Sun 16 Nov 2025, Tampa Bay Buccaneers at Buffalo Bills: the Bills won 44-32.

DateGameScoreWinner
16 Nov 2025Tampa Bay Buccaneers @ Buffalo Bills44–32Buffalo Bills
26 Oct 2023Tampa Bay Buccaneers @ Buffalo Bills24–18Buffalo Bills
12 Dec 2021Buffalo Bills @ Tampa Bay Buccaneers33–27Tampa Bay Buccaneers
22 Oct 2017Tampa Bay Buccaneers @ Buffalo Bills30–27Buffalo Bills

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