Detroit Lions vs New England Patriots Prediction & Picks, November 15, 2026

The Detroit Lions are playing at home against the New England Patriots, which gives them a nice boost. They've shown strong form lately, especially on offense, and they're looking to keep that momentum going. The Lions have a good chance to win this game, and their fans will surely be loud and supportive at Ford Field. However, the Patriots are no slouches and can be tricky opponents. Their defense might cause some trouble for the Lions, especially if they can find a way to slow down the Lions' playmakers. Still, with the Lions playing at home and our numbers rating their chances as good, this bet looks promising.

Detroit Lions vs New England Patriots: Under 23.5 Team Total Points (+100)

The Detroit Lions have been strong lately, but they face a tough challenge against the New England Patriots. Both teams have solid defenses, which could make it hard for either side to score a lot of points. The Lions' offense has shown some spark, but the Patriots know how to slow down high-scoring games. Betting on the Lions to score under 23.5 points seems reasonable given the matchup. The defenses are both capable of holding their ground, and this game is rated close to a coin flip. The biggest risk is that both teams might find ways to score more than expected, but the chance of a low-scoring game feels good here.

Detroit Lions vs New England Patriots: Hunter Henry Over 35.5 Receiving Yards (-110)

The Lions have a solid defense, but the Patriots will likely lean on Hunter Henry in the passing game. With the way the Lions play, they might give Henry a chance to get open, especially since the Patriots could be looking for short, reliable throws from their quarterback. Betting on Henry to get over 35.5 receiving yards seems reasonable given this matchup. Despite the close nature of the teams, Henry has been getting plenty of targets, which increases his chances to rack up those yards. The biggest risk is that the Patriots' offense could struggle if they don't find their rhythm, but Henry has shown he can step up when needed.

Detroit Lions vs New England Patriots: Hunter Henry Over 35.5 Receiving Yards (Alt) (-110)

The Patriots are facing the Lions, and it's a tough matchup for them. Detroit's defense has been known to struggle against tight ends, which is where Hunter Henry shines. He has a good chance to get open and make some big plays, especially since the Lions might be focusing on the Patriots' wide receivers. Betting on Henry to get over 35.5 receiving yards feels like a solid choice. Both teams are pretty close in skill, making it a bit tricky. The biggest risk here is that if the Patriots run the ball a lot, Henry might not see as many targets. Still, with the Lions' defense likely giving him some space, he could easily break that mark.

Detroit Lions vs New England Patriots: Jahmyr Gibbs Under 93.5 Rushing Yards (-110)

The Detroit Lions have a strong offense, but the New England Patriots' defense is known for being tough against the run. Jahmyr Gibbs has shown talent, but with the Patriots focused on stopping the ground game, it might be hard for him to rack up rushing yards. Playing at home gives the Lions an advantage, but that doesn't guarantee Gibbs will break through. Betting on Gibbs to go under 93.5 rushing yards feels wise here, especially since our numbers rate it as close to a coin flip. The Patriots have a solid chance to limit his output, making this a risky bet. If the Patriots can force the Lions to pass more, Gibbs may not get the chances he needs.

That is everything our model likes in this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.