Baltimore Orioles vs Toronto Blue Jays Prediction and Picks, September 23, 2026

Both the Baltimore Orioles and Toronto Blue Jays have struggled lately, but they can put runs on the board. The Orioles have won 5 of their last 10 games, though they've lost their last 3 at home. Meanwhile, the Blue Jays have not been much better, winning just 4 of their last 10, but they have found some success away from home, winning 5 of their last 8 games. With both teams having the potential to score, I think betting on over 7.5 total runs makes sense. Our numbers suggest a combined total of around 9 runs, so this bet feels like a solid option. The biggest risk is how closely matched these teams are right now, which could lead to a tighter game than expected.

Baltimore Orioles vs Toronto Blue Jays: Baltimore Orioles -1.5 Spread (+172)

The Baltimore Orioles have been a bit shaky recently, losing three straight games at home. However, they've also shown some fight by winning three of their last six, so they could be ready to turn things around. Facing the Toronto Blue Jays, who have won only two of their last six, the Orioles have a decent chance to take this game. Betting on the Orioles to win by at least two runs feels like a smart choice since they're playing at home and have a strong record there overall. The risk is that the teams are very close in skill, so this one could go either way. Still, with the Orioles looking to bounce back, they might just pull off a solid win.

That is the full board for this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.