Los Angeles Dodgers vs San Diego Padres Prediction and Picks, September 23, 2026

The San Diego Padres are on a hot streak, winning 9 of their last 10 games, which shows they're in great form. They've also been strong on the road, winning 5 of their last 6 away games. Meanwhile, the Dodgers have won 7 of their last 10 but have been less dominant recently. Betting on the Padres to win here is a solid choice since they are the underdogs with a real shot at taking this game. The biggest risk is that the Dodgers have been strong at home, winning 5 of their last 6. Still, the Padres' recent success makes them a team to watch.

Los Angeles Dodgers vs San Diego Padres: San Diego Padres +1.5 Spread (-118)

The San Diego Padres are coming into this game on a hot streak, having won 9 of their last 10 matches. They've also done well on the road, winning 5 of their last 6 games. Meanwhile, the Dodgers have been strong too, but this matchup is tight since both teams have been performing well recently. Betting on the Padres to keep it close with a spread of +1.5 seems like a solid choice. The odds are nearly even, and our numbers suggest the final margin will be just a little more than half a run. The biggest risk is how well the Dodgers have been ahead after five innings in many of their games, but the Padres have shown they can compete.

Los Angeles Dodgers vs San Diego Padres: Over 8.5 Total Runs (+100)

The odds for over 8.5 total runs are looking pretty good at even money. The Dodgers have been strong lately, winning 7 of their last 10 games and scoring well to keep the action alive. Meanwhile, the Padres are also on a roll, winning 9 of their last 10. With both teams hitting well, we could see a lot of runs today. The Dodgers have often been ahead after five innings in their games, showing they can put up numbers early. However, the biggest risk here is that both teams are closely matched right now. Still, with our numbers suggesting a combined total of about 8.7 runs, this bet has a decent chance to pay off.

Los Angeles Dodgers vs San Diego Padres: Freddie Freeman Over 1.5 Batter - Hits + Runs + RBIs (-110)

Freddie Freeman has been on fire lately, hitting the ball hard and at the right angle more often than most players. The Dodgers are playing at home, where they've won five of their last six games, and overall, they've taken seven of their last ten. That gives them a good chance to score runs, boosting Freeman's chances for hits, runs, and RBIs. However, the Padres' starting pitcher has been allowing nearly five runs every nine innings, which is a bit higher than average. This could lead to more scoring opportunities for Freeman. While it's a close matchup, I think he can definitely get over 1.5 combined hits, runs, and RBIs today.

Los Angeles Dodgers vs San Diego Padres: Jake Cronenworth Over 0.5 Batter - Hits (-125)

The Dodgers are in great form, winning 7 of their last 10 games, and they've been particularly strong at home lately. On the other hand, the Padres have also been impressive, winning 9 of their last 10. Tonight, the wind is blowing out toward the outfield, which is good news for hitters like Jake Cronenworth, who has been getting hits about 1.3 times more frequently than usual. While Cronenworth has a challenging matchup, he's still got a solid chance to get at least one hit. The competition is close, and the Padres' recent success makes this a bit tricky. But with the right conditions and his good hitting form, he could come through for us tonight.

Los Angeles Dodgers vs San Diego Padres: Jake Cronenworth Over 0.5 Batter - Singles (+130)

The Dodgers are looking strong lately, winning 7 out of their last 10 games. They've been in front after five innings in a lot of their matchups, showing they can keep the pressure on. Meanwhile, the Padres have also been on a roll, winning 9 of their last 10 games, so this matchup is pretty tight. Jake Cronenworth is hitting well, getting hits about 1.3 times more often than usual right now. With the wind blowing out toward the outfield, it could help him get a single. The biggest concern is that both teams are playing at a high level, which might make it challenging. Still, with Cronenworth's current form, betting on him to get at least one single feels like a solid choice.

That is everything our model likes in this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.