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Odds and preview
NBA
Thu 22 Oct 2026, 7:10PM ET
Cleveland Cavaliers
VS
Philadelphia 76ers

Cleveland Cavaliers vs Philadelphia 76ers prediction and odds · Thu 22 Oct

Philadelphia 76ers host Cleveland Cavaliers on Thursday 22 October.

Philadelphia 76ers host Cleveland Cavaliers on Thursday 22 October. The bookies' opening prices make the 76ers about a 6 in 10 chance to win. If our model picks this game, the pick lands here before kickoff.

Cleveland Cavaliers vs Philadelphia 76ers odds

Prices for this game

Best opening price: 76ers paid $1.77, Cavaliers paid $2.50 (the best of 40 bookies). Prices change before kickoff.

Fair chance at the open (our read of the prices, with the bookies' cut taken out): 76ers about 6 in 10, Cavaliers about 4 in 10.

How much the bookies keep: about $4.80 of every $100 bet on this game.

Since betting opened: the price has barely moved.

Prices from when betting opened on Thu 8 Oct
Our pick for this game

If our model picks this game, the pick lands here before kickoff. Today's NBA picks are already up: see today's NBA picks.

Injuries & who's out

Injuries & availability

Cleveland Cavaliers

  • Nae'Qwan Tomlin FDay-to-day
  • Sam Merrill GDay-to-day
  • Khalifa Diop CDay-to-day

Philadelphia 76ers

  • Dominick Barlow FDay-to-day
  • Tacko Fall CDay-to-day
  • Dean Wade FDay-to-day
  • VJ Edgecombe GDay-to-day
  • Anfernee Simons GDay-to-day
  • Adem Bona CDay-to-day
  • Ariel Hukporti COut
Availability updated Oct 17, 2:15AM UTC · refreshed roughly every 4 hours.

Cleveland Cavaliers vs Philadelphia 76ers head-to-head record

Final scores · 3 meetings on record
Cleveland Cavaliers 3–0 across the last 3 meetings

Last meeting: Mon 9 Mar 2026, Philadelphia 76ers at Cleveland Cavaliers: the Cavaliers won 115-101.

DateGameScoreWinner
9 Mar 2026Philadelphia 76ers @ Cleveland Cavaliers115–101Cleveland Cavaliers
17 Jan 2026Cleveland Cavaliers @ Philadelphia 76ers115–117Cleveland Cavaliers
15 Jan 2026Cleveland Cavaliers @ Philadelphia 76ers107–133Cleveland Cavaliers
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