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Model picks & player props
Arizona Cardinals
VS
Los Angeles Chargers

Arizona Cardinals vs Los Angeles Chargers Picks & Predictions

Model updated Sep 20, 4:37AM UTC

Our model graded 68 markets for Arizona Cardinals vs Los Angeles Chargers and backs Over 27.5 hardest, a lean, and $100 on it returns about $285.

NFL
Los Angeles
Sun 13 Sep 2026, 8:25PM
20
Game markets graded
48
Props graded
The model's one call for this gamethe prediction, first
Over 27.5 Alternate Totals H2 +185

The model graded 68 markets for Arizona Cardinals vs Los Angeles Chargers (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $285 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 13 Sep 2026, 8:25PM at Los Angeles.

Our confidenceLean
Chance to win43.7%
The price says33.1%
Best price+185
The rest of this game's boardgraded market by market
Alternate Totals H2 Over 27.5 Lean44% chance +185
Alternate Totals H2 Members only Long-shot40% chance Members
Totals Q4 Members only Lean58% chance Members
Moneyline Q2 Members only Long-shot37% chance Members
Alternate Team Totals H1 Members only Long-shot36% chance Members
Alternate Totals H1 Members only Lean49% chance Members
Moneyline Members only Long-shot23% chance Members
Moneyline Q1 Members only Long-shot37% chance Members
Alternate Spreads H2 Members only Long-shot36% chance Members
Receiving Yards (Alt) × 3 props Highup to 95% Members
Receptions × 4 props Highup to 78% Members
Receiving Yards × 3 props Highup to 73% Members
Last Touchdown Scorer × 11 props Long-shotup to 38% Members
Rushing Attempts (Alt) × 1 prop Leanup to 41% Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

Arizona Cardinals and Los Angeles Chargers last met on Sun 13 Sep 2026. The model's calls from that game are graded below. Today's board: every NFL game priced right now.

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This game is done — from the model’s graded calls on this game
Arizona Cardinals · $100 returned $517

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This gameBets like this sit in our formula’s best NFL market — 174 of 355 right (nfl alternate team total points overs)
This bet type · last timeSep 15
Kansas City Chiefs Over 17.5
Denver Broncos @ Kansas City Chiefs
CASHED
STAKE $100RETURNS $136
Our call on this game: — members only · unlock tonight's call2 picks on the board · logged before tip-offSee the picks

Game picks

GOOD PRICE in green
Alternate Totals H2
Over
16.5
-435
+ 19 more markets
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All 20 game markets and 48 player props for this matchup — every line, every call the model backs — plus every pick across the slate. Join 57,537+ members.

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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
OverAlternate Totals H2The model likes this price 🔒 Unlock with Pro
OverAlternate Totals H2The model likes this price 🔒 Unlock with Pro
OverAlternate Totals H2The model likes this price 🔒 Unlock with Pro
OverAlternate Totals H2The model likes this price 🔒 Unlock with Pro
OverTotals Q4The model likes this price 🔒 Unlock with Pro
Arizona CardinalsMoneyline Q2The model likes this price 🔒 Unlock with Pro
OverAlternate Team Totals H1The model likes this price 🔒 Unlock with Pro
UnderAlternate Totals H1The model likes this price 🔒 Unlock with Pro
Arizona CardinalsMoneylineThe model likes this price 🔒 Unlock with Pro
Arizona CardinalsMoneyline Q1The model likes this price 🔒 Unlock with Pro
OverAlternate Totals H2The model likes this price 🔒 Unlock with Pro
Arizona CardinalsAlternate Spreads H2The model likes this price 🔒 Unlock with Pro
Arizona CardinalsAlternate Spreads H2The model likes this price 🔒 Unlock with Pro
OverAlternate Totals H1The model likes this price 🔒 Unlock with Pro
Arizona CardinalsMoneyline Q3The model likes this price 🔒 Unlock with Pro
OverAlternate Team Totals H1The model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

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Injuries & who's out

Injuries & availability

Arizona Cardinals

  • Isaac Seumalo GQuestionable
  • Isaiah Adams GQuestionable
  • Andrew Billings DTQuestionable
  • Roy Lopez DTQuestionable
  • Max Melton CBQuestionable
  • Dadrion Taylor-Demerson SQuestionable
  • Garrett Williams CBOut
  • Kitan Crawford SOut
  • Kaleb Proctor DTOut

Los Angeles Chargers

  • Trey Pipkins III OTOut
  • Elijah Molden CBOut
  • Deane Leonard CBQuestionable
  • Ladd McConkey WRQuestionable
  • KeAndre Lambert-Smith WROut
Availability updated Sep 19, 1:53AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Arizona Cardinals vs Los Angeles Chargers: Weather isn't a tracked factor for this fixture, and 14 players are listed out or questionable across both sides.
FactorThis fixture
Availability14 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

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Player props

GOOD PRICE in green
PlayerTeamStat
Ladd McConkey LAC Receiving Yards (Alt)
Quentin Johnston LAC Receptions
Ladd McConkey LAC Receiving Yards
Quentin Johnston LAC Last Touchdown Scorer
Quentin Johnston LAC Receiving Yards

+ 48 player props graded for this game — the line, the call and how much to put on each, with Pro.

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Betting angles

Markets & form
MoneylineArizona Cardinals to winNo line posted

Arizona Cardinals vs Los Angeles Chargers moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadLos Angeles Chargers spreadNo line posted

Los Angeles Chargers vs Arizona Cardinals spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total PointsCardinals @ ChargersNo line posted

Los Angeles Chargers vs Arizona Cardinals game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Arizona Cardinals @ Los Angeles Chargers — what the model found

Our model graded 68 betting markets for Arizona Cardinals at Los Angeles Chargers — 20 on the game itself and 48 on individual players. One pick is free on this page.

20
Game markets graded
48
Player bets graded

The model checked every betting market for this game and graded 68 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 67 graded calls for this game — with how much to bet on each — are for members.
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Arizona Cardinals vs Los Angeles Chargers — recent results

Los Angeles Chargers have won 1 of their last 5 games; Arizona Cardinals have won 2 of their last 5.

Los Angeles Chargers — last 5
ResultScoreOpponentWhere
L14–26ARIHome
L18–20LARHome
L17–41SFHome
W27–7HOUAway
L3–16NEAway
Arizona Cardinals — last 5
ResultScoreOpponentWhere
W26–14LACAway
L38–42GBAway
L13–34DALHome
W27–14LVAway
L30–33CARHome

Arizona Cardinals vs Los Angeles Chargers — recent meetings

These two have met 1 time recently: Los Angeles Chargers won 0, Arizona Cardinals won 1.

DateLos Angeles ChargersArizona CardinalsWinner
Sep 131426Arizona Cardinals

Who’s out or in doubt

14 players are listed as out or in doubt for this game.

Los Angeles Chargers
PlayerStatus
Trey Pipkins III OTOUT
Elijah Molden CBOUT
Deane Leonard CBQUESTIONABLE
Ladd McConkey WRQUESTIONABLE
KeAndre Lambert-Smith WROUT
Arizona Cardinals
PlayerStatus
Isaac Seumalo GQUESTIONABLE
Isaiah Adams GQUESTIONABLE
Andrew Billings DTQUESTIONABLE
Roy Lopez DTQUESTIONABLE
Max Melton CBQUESTIONABLE
Dadrion Taylor-Demerson SQUESTIONABLE
Garrett Williams CBOUT
Kitan Crawford SOUT

The full availability report — with what each missing player means for the bets — is further down this page.

Cashed picks for this matchup

From the public log
DateMarketPickResult
13 Sep 26 Moneyline Q2 Arizona Cardinals ✓ HIT
13 Sep 26 Alternate Totals H1 Under 22.5 ✓ HIT
13 Sep 26 Alternate Totals H2 Over 16.5 ✓ HIT
13 Sep 26 Moneyline Arizona Cardinals ✓ HIT
13 Sep 26 Alternate Spreads H2 Arizona Cardinals 0.5 ✓ HIT
13 Sep 26 Alternate Spreads H2 Arizona Cardinals 1.5 ✓ HIT
13 Sep 26 Alternate Totals H2 Over 19.5 ✓ HIT
13 Sep 26 Alternate Totals H2 Over 18.5 ✓ HIT
13 Sep 26 Alternate Spreads H2 Arizona Cardinals 2.5 ✓ HIT
13 Sep 26 Alternate Spreads H2 Arizona Cardinals -1.5 ✓ HIT

Every pick — wins and losses — is logged on the public record.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Arizona Cardinals vs Los Angeles Chargers in the NFL. You may also see this matchup written as Cardinals vs Chargers, or as Chargers vs Cardinals. The most recent game between them was Sunday 13 September 2026 at Los Angeles. The model has generated 20 game picks and 48 player props for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Head-to-head record

Final scores · 4 meetings on record
Even at 2–2 across the last 4 meetings · these games average 44.0 points (meetings on record since 2018)
DateGameScoreWinner
13 Sep 2026Arizona Cardinals @ Los Angeles Chargers14–26Arizona Cardinals
21 Oct 2024Los Angeles Chargers @ Arizona Cardinals17–15Arizona Cardinals
27 Nov 2022Los Angeles Chargers @ Arizona Cardinals24–25Los Angeles Chargers
25 Nov 2018Arizona Cardinals @ Los Angeles Chargers45–10Los Angeles Chargers

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