Minnesota Twins vs Chicago White Sox Prediction and Picks, August 29, 2026

The Chicago White Sox have been strong at home and are playing well lately, winning five of their last ten games. They hit left-handed pitchers really well, with a solid average that's better than what most teams manage. The Twins, on the other hand, have struggled a bit at home, winning just over half their games there. While this matchup is pretty close overall, the White Sox seem to have a slight advantage. The Twins' hitting against lefties isn't quite as good as the White Sox's, which could make a difference. The biggest risk is that both teams have been inconsistent, but the White Sox look ready to take this one.

Minnesota Twins vs Chicago White Sox: Under 9.5 Total Runs (-118)

For this game to go under 9.5 total runs, both teams need to have a pretty quiet night at the plate. The Twins have struggled lately, winning just 4 of their last 10 games, and their hitting against left-handed pitchers has been average at best. The White Sox have a decent record at home but have been iffy on the road, and while they hit well against lefties, they might find it hard to score big at Target Field. The key risk is that both teams are fairly close in their recent form, which could lead to some back-and-forth scoring. However, our numbers suggest a combined total around 7.5 runs, making the under look promising. With both teams not on fire and the pitching matchup likely favoring the pitchers, there's a good chance this game stays low-scoring.

Minnesota Twins vs Chicago White Sox: Chicago White Sox -1.5 Spread (+164)

The Chicago White Sox have been pretty solid on the road, winning 41 of their games at home and showing good hitting against left-handed pitchers this season. Meanwhile, the Minnesota Twins have struggled a bit more at home, only winning 35 out of 66 games there and hitting close to average against lefties. This matchup features two teams that have been somewhat inconsistent lately, with both winning about half their recent games. The risk here is that the Twins can sometimes surprise at home, but the White Sox's strong batting against lefties gives them a good chance to cover the spread. Overall, with the numbers looking favorable for Chicago, this bet seems like a smart pick.

That is our read — no bet on this board is a sure thing. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.