On Saturday 19 September 2026, Louisville Cardinals play SMU Mustangs in college football. Our model likes 6 bets here. The one it likes most is SMU Mustangs +2 on the Line, priced at -110 when we wrote this. Here is the thinking behind each pick, in plain English.
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is SMU Mustangs 2 Point Spread. On this line SMU Mustangs start with 2 points in hand, so they can lose by less than that and this still wins. This is one of the bookmaker's alternate lines, not the main one, so the price is different. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at Fanatics. Our model leans this way, without being sure. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The number next to the team is the handicap, and that team's score is adjusted by it before the bet is settled. This is an alternate line, so it is not the main number on the board and the price moves with it. The bookmakers have this as a slight favourite. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
SMU Mustangs to Win (+110)
Odds available at Bovada at time of publishing
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is SMU Mustangs Moneyline. This one only needs SMU Mustangs to win the game. It was priced at +110 when we wrote this, so a $10 bet returns $21 if it lands. That price was showing at Bovada. Our model leans this way, without being sure. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at +110 when we wrote this, so a $10 bet returns $21 if it lands. This one is priced as an outside chance. Our model has this as a long shot, so keep the stake small. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
Under 58.5 Total Points (-108)
Odds available at William Hill at time of publishing
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is Under 58.5 Total Points. This wins if the two sides score fewer than 58.5 points between them. This is one of the bookmaker's alternate lines, not the main one, so the price is different. It was priced at -108 when we wrote this, so a $10 bet returns $19.26 if it lands. That price was showing at William Hill. Our model leans this way, without being sure. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -108 when we wrote this, so a $10 bet returns $19.26 if it lands. This is an alternate line, so it is not the main number on the board and the price moves with it. The bookmakers have this as a slight favourite. Our model leans this way without loving it. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
Lawayne McCoy Over 37.5 Receiving Yards (-110)
Odds available at BetOnline at time of publishing
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is Lawayne McCoy Over 37.5 Receiving Yards. This wins if Lawayne McCoy finishes with more than 37.5 receiving yards. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at BetOnline. Our model likes this one a lot. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The bookmakers have this as a slight favourite. Our model leans this way without loving it. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
Kevin Jennings Under 289.5 Passing Yards (-110)
Odds available at BetOnline at time of publishing
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is Kevin Jennings Under 289.5 Passing Yards. This wins if Kevin Jennings finishes with fewer than 289.5 passing yards. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at BetOnline. Our model leans this way, without being sure. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The bookmakers have this as a slight favourite. Our model leans this way without loving it. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
Keyjuan Brown Over 39.5 Rushing Yards (-110)
Odds available at BetOnline at time of publishing
On Saturday 19 September 2026, Louisville Cardinals host SMU Mustangs in college football. The bet we are looking at is Keyjuan Brown Over 39.5 Rushing Yards. This wins if Keyjuan Brown finishes with more than 39.5 rushing yards. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at BetOnline. Our model likes this one a lot. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The bookmakers have this as a slight favourite. Our model leans this way without loving it. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
That is how our model reads Louisville Cardinals v SMU Mustangs. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.