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Model picks & player props
NCAAF
Sat 17 Oct 2026, 7:30 PM ET
Louisville Cardinals
VS
Syracuse Orange

Louisville Cardinals vs Syracuse Orange Prediction & Picks

Our model graded 23 markets for Louisville Cardinals vs Syracuse Orange and backs Louisville Cardinals -14.5 hardest, a lean, and $100 on it returns about $194.

12
Game markets graded
11
Props graded
The model's one call for this gamethe prediction, first Free
Louisville Cardinals
to win by 15+ points
Louisville Cardinals -14.5 Spread
You bet$10 If it wins$19.43Best price-106
Our confidenceLean
Chance to win47.7%
The price says50.0%

The model graded 23 markets for Louisville Cardinals vs Syracuse Orange (NCAAF) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $194 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sat 17 Oct 2026, 7:30 PM ET.

This game's bets

The rest of this game's boardgraded market by market
Spread Louisville Cardinals -14.5 Lean48% chance -106
Spread Members only Lean48% chance Members
Total Points Members only Lean46% chance Members
Moneyline Members only Lean54% chance Members
Receptions × 1 prop Highup to 100% Members
Passing Yards × 2 props Highup to 99% Members
Rushing Yards × 2 props Highup to 90% Members
Receiving Yards × 6 props Leanup to 57% Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%

Louisville Cardinals and Syracuse Orange last met on Sat 17 Oct 2026: Louisville Cardinals won 34-26. Their next game gets a fresh preview here the moment it is priced. Today's board: every NCAAF game priced right now.

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Game picks

GOOD PRICE in green
Spread
Louisville Cardinals
-14.5
+ 11 more markets
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All 12 game markets and 11 player props for this matchup — every line, every call the model backs — plus every pick across the slate. Join 73,413+ members.

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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsSpreadThe model likes this price 🔒 Unlock with Pro
OverTotal PointsThe model likes this price 🔒 Unlock with Pro
OverTotal PointsThe model likes this price 🔒 Unlock with Pro
Louisville CardinalsMoneylineThe model likes this price 🔒 Unlock with Pro
OverTotal PointsThe model likes this price 🔒 Unlock with Pro

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Injuries & who's out

Injuries & availability

Louisville Cardinals

No players are currently listed out or questionable for this team.

Syracuse Orange

No players are currently listed out or questionable for this team.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Louisville Cardinals vs Syracuse Orange: Weather isn't a tracked factor for this fixture, and no players are currently listed out or questionable.
FactorThis fixture
AvailabilityNone currently listed out or questionable

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Player props

GOOD PRICE in green
PlayerTeamStat
Umari Hatcher Syracuse Receptions
Malachi Nelson Syracuse Passing Yards
Lincoln Kienholz Louisville Rushing Yards
Lincoln Kienholz Louisville Passing Yards
Tylik Hill Syracuse Rushing Yards

+ 11 player props graded for this game — the line, the call and how much to put on each, with Pro.

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Louisville Cardinals @ Syracuse Orange — what the model found

Our model graded 23 betting markets for Louisville Cardinals at Syracuse Orange — 12 on the game itself and 11 on individual players. One pick is free on this page.

12
Game markets graded
11
Player bets graded

The model checked every betting market for this game and graded 23 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 22 graded calls for this game — with how much to bet on each — are for members.
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Louisville Cardinals @ Syracuse Orange — model preview

Syracuse Orange v Louisville Cardinals, 17 October 2026. Top of the list: Over 55.5 Total Points. Our model likes 6 bets in this game.

On Saturday 17 October 2026, Syracuse Orange play Louisville Cardinals in college football. Our model likes 6 bets here. The one it likes most is Over 55.5 Total Points, priced at -110 when we wrote this. Here is the thinking behind each pick, in plain English.

Over 55.5 Total Points (-110)

Odds correct at time of publishing

On Saturday 17 October 2026, Syracuse Orange host Louisville Cardinals in college football. The bet we are looking at is Over 55.5 Total Points. This wins if the two sides score more than 55.5 points between them. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at William Hill. Our model leans this way, without being sure. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The bookmakers have this as a slight favourite. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

🔒 The other 5 write-ups for this game — with how much to bet on each — are Pro.
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About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Louisville Cardinals vs Syracuse Orange in the NCAAF. You may also see this matchup written as Cardinals vs Orange, or as Orange vs Cardinals. The most recent game between them was Saturday 17 October 2026. The model has generated 12 game picks and 11 player props for this matchup. Review the picks and historical data above to guide your NCAAF betting strategy for this matchup.

Louisville Cardinals vs Syracuse Orange: game facts

Past meetings and recent results

Where they last met

  • 17 Oct 2026Louisville Cardinals beat Syracuse Orange 34-26 on the road

Louisville Cardinals: last 5 results

  1. 31 Oct 2026Wonvs Stanford Cardinal 52-24
  2. 17 Oct 2026Wonat Syracuse Orange 34-26
  3. 9 Oct 2026Wonvs Florida State Seminoles 44-20
  4. 3 Oct 2026Lostat NC State Wolfpack 28-31
  5. 26 Sep 2026Lostvs Wake Forest Demon Deacons 27-30

Syracuse Orange: last 5 results

  1. 31 Oct 2026Wonvs SMU Mustangs 30-27
  2. 24 Oct 2026Wonat North Carolina Tar Heels 31-30
  3. 17 Oct 2026Lostvs Louisville Cardinals 26-34
  4. 10 Oct 2026Lostat Virginia Cavaliers 25-28
  5. 3 Oct 2026Wonat UConn Huskies 42-41

Quick answers

Who won the last Syracuse Orange vs Louisville Cardinals game? Louisville Cardinals won their last meeting 34-26 on 17 October 2026.

How have Louisville Cardinals and Syracuse Orange done lately? Louisville Cardinals won 3 and lost 2 of the last 5 results we hold. Syracuse Orange won 3 and lost 2 of the last 5 results we hold.

From the final scores we hold. Newest game first.

Louisville Cardinals vs Syracuse Orange head-to-head record

Final scores · 1 meeting
Louisville Cardinals 1–0 across the last meeting

Last meeting: Sat 17 Oct 2026, Louisville Cardinals at Syracuse Orange: Louisville Cardinals won 34-26.

DateGameScoreWinner
17 Oct 2026Louisville Cardinals @ Syracuse Orange26–34Louisville Cardinals
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