Seattle Seahawks vs Arizona Cardinals Prediction & Picks, November 8, 2026

The Arizona Cardinals are underdogs against the Seattle Seahawks, but they have a real shot to win. The Seahawks have struggled lately, and the Cardinals are hungry for a victory. Arizona's offense can put points on the board, and they might catch the Seahawks' defense off guard. The biggest risk here is that the game is being played in Seattle, where the crowd can be loud and tough for the visiting team. Still, the Cardinals have shown they can compete, and at these odds, taking a chance on them could pay off.

Seattle Seahawks vs Arizona Cardinals: Over 24.5 Team Total Points (-108)

The Seattle Seahawks have a strong offense, especially when they play at home. With their quarterback in good form, they can really rack up points against the Arizona Cardinals. The Cardinals have struggled defensively, which gives Seattle a solid shot at scoring more than 24 points in this game. While both teams are closely matched, the Seahawks' ability to put points on the board makes this a promising bet. The biggest risk is that the Cardinals might surprise us with a better defensive performance than expected. Still, with the Seahawks' home advantage and their offensive talent, taking the over on 24.5 points feels like a smart move.

Seattle Seahawks vs Arizona Cardinals: Drew Lock Under 4.5 Rushing Yards (-110)

For this game, Drew Lock needs to rush for less than 4.5 yards. This is likely because the Seahawks have a strong defense that can stop the run. Lock hasn't been known for his rushing ability, and with the Cardinals likely focusing on shutting him down, it makes it harder for him to gain yards on the ground. A major risk is that Lock might try to scramble if the pocket collapses, but overall, our numbers give this bet a good chance. With both teams battling hard, Lock's rushing might not be a big part of the game plan, making the under a solid choice.

Seattle Seahawks vs Arizona Cardinals: Cooper Kupp Under 2.5 Receptions (+112)

For the bet to hit tonight, Cooper Kupp needs to catch fewer than three passes against the Arizona Cardinals. While Kupp is a talented receiver, the Cardinals have a tough defense that can shut down opponents. Plus, the game is quite evenly matched, making it tricky for anyone to stand out. Kupp's recent form has been a bit shaky, and with the Cardinals focusing on limiting his impact, he might struggle to get open. The fact that this game is so close means either team could win, and that makes it hard to predict how many passes Kupp will catch. It's a bit risky, but the odds are decent for this outcome.

Seattle Seahawks vs Arizona Cardinals: Drew Lock Under 1.5 Passing Touchdowns (-106)

For this bet to work out, Drew Lock needs to throw fewer than two passing touchdowns against the Arizona Cardinals. The Cardinals' defense has been pretty tough, making it hard for quarterbacks to rack up points. Lock's performance has been up and down lately, so it feels like a close match-up tonight. The risk here is that both teams are fairly evenly matched, which could lead to a surprising offensive showing. However, given how well Arizona's defense has played against the pass, it's likely that Lock will struggle to find the end zone through the air. This makes the under on his passing touchdowns a solid pick for this game.

That is everything our model likes in this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.