Atlanta Falcons vs San Francisco 49ers Prediction & Picks, October 25, 2026

The Atlanta Falcons have a strong running game but struggle with their passing attack. Jordan Watkins, who hasn't been a primary target in the offense, only saw a small portion of the team's air yards last season. With the Falcons' quarterback facing extra rushers often, this could make it tough for him to connect on deeper throws. On the other hand, the San Francisco 49ers have a solid defense that can pressure quarterbacks effectively. Since Watkins has been targeted so little, betting on him to get more than 24.5 receiving yards feels risky. There's a good chance he stays under that mark, especially with how the teams match up.

Atlanta Falcons vs San Francisco 49ers: Kaelon Black Under 27.5 Rushing Yards (-111)

For this bet to win, Kaelon Black needs to rush for less than 27.5 yards tonight. The Falcons have struggled with their running game, gaining better results when they throw the ball instead. In fact, they had a tough time gaining points per rush last season, which makes it likely that Black won't have a big night on the ground. The 49ers defense is also solid at stopping the run, making things even tougher for him. While Black may get some chances, the Falcons' offense has shown they rely more on passing than rushing, which could limit his yardage. Since this matchup is pretty close, the risk is that Black could have a surprising game, but with the overall trends, the under seems like a smart pick.

Atlanta Falcons vs San Francisco 49ers: Kyle Juszczyk Under 11.5 Receiving Yards (-111)

Kyle Juszczyk has been quiet lately, and that makes this bet interesting. He's not been getting many targets, and the Atlanta Falcons have been better at stopping plays through the air than on the ground. Plus, their defense can put pressure on the quarterback, which might limit how often he gets the ball. While Kyle can break out for a big play, the Falcons' focus on running the ball more means he might not have many chances. The biggest risk here is that the 49ers' quarterback has faced fewer extra rushers compared to Kyle's situation, so it could be close. Still, betting on Kyle Juszczyk to have under 11.5 receiving yards seems like a smart play right now.

That is the whole read on this one. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.