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NFL predictions for Sunday, September 27: the model backs Cowboys

14 NFL games on Sunday. The model's strongest pick is Cowboys +3, a HIGH-confidence call. 7 more games have a HIGH-confidence pick.

By Marcus Cole · Published Sep 26, 12:00 AM ET · Updated Sep 27, 12:58 PM ET

Written with our model's data and an AI writing assistant, checked against our rules. Meet our writers

These were our picks for Sunday, September 27. See today's NFL predictions

Los Angeles Chargers at Buffalo Bills

Sun Sep 27, 1:00 PM ET
Our pick: Bills -7 (they must win by 8 or more; win by exactly 7 and your stake comes back)-112

HIGH — about a 6 in 10 chance by our numbers

Full Los Angeles Chargers at Buffalo Bills preview →

Carolina Panthers at Cleveland Browns

Sun Sep 27, 1:00 PM ET
Our pick: Over 42.5 points-108

LEAN — about a 6 in 10 chance by our numbers

Cleveland's offense has been solid, and they should find ways to score against Carolina's defense.

Full Carolina Panthers at Cleveland Browns preview →

New York Jets at Detroit Lions

Sun Sep 27, 1:00 PM ET
New York Jets at Detroit Lions · Spread Which side the model backs, and why · Pro
Full New York Jets at Detroit Lions preview →

Houston Texans at Indianapolis Colts

Sun Sep 27, 1:00 PM ET
Houston Texans at Indianapolis Colts · Total Points Which side the model backs, and why · Pro
Full Houston Texans at Indianapolis Colts preview →

New England Patriots at Jacksonville Jaguars

Sun Sep 27, 1:00 PM ET
New England Patriots at Jacksonville Jaguars · Total Points Which side the model backs, and why · Pro
Full New England Patriots at Jacksonville Jaguars preview →

Kansas City Chiefs at Miami Dolphins

Sun Sep 27, 1:00 PM ET
Kansas City Chiefs at Miami Dolphins · Spread Which side the model backs, and why · Pro
Full Kansas City Chiefs at Miami Dolphins preview →

Tennessee Titans at New York Giants

Sun Sep 27, 1:00 PM ET
Tennessee Titans at New York Giants · Total Points Which side the model backs, and why · Pro
Full Tennessee Titans at New York Giants preview →

Cincinnati Bengals at Pittsburgh Steelers

Sun Sep 27, 1:00 PM ET
Cincinnati Bengals at Pittsburgh Steelers · Total Points Which side the model backs, and why · Pro
Full Cincinnati Bengals at Pittsburgh Steelers preview →

Seattle Seahawks at Washington Commanders

Sun Sep 27, 1:00 PM ET
Seattle Seahawks at Washington Commanders · Spread Which side the model backs, and why · Pro
Full Seattle Seahawks at Washington Commanders preview →

Arizona Cardinals at San Francisco 49ers

Sun Sep 27, 4:05 PM ET
Arizona Cardinals at San Francisco 49ers · Spread Which side the model backs, and why · Pro
Full Arizona Cardinals at San Francisco 49ers preview →

Minnesota Vikings at Tampa Bay Buccaneers

Sun Sep 27, 4:05 PM ET
Minnesota Vikings at Tampa Bay Buccaneers · Total Points Which side the model backs, and why · Pro
Full Minnesota Vikings at Tampa Bay Buccaneers preview →

Baltimore Ravens at Dallas Cowboys

Sun Sep 27, 4:25 PM ET
Top pick: Cowboys +3 (they can lose by up to 2 and the bet still wins; lose by exactly 3 and your stake comes back)-110

HIGH — about a 7 in 10 chance by our numbers

The Dallas Cowboys have a solid shot at covering the spread against the Baltimore Ravens.

Full Baltimore Ravens at Dallas Cowboys preview →

Las Vegas Raiders at New Orleans Saints

Sun Sep 27, 4:25 PM ET
Las Vegas Raiders at New Orleans Saints · Total Points Which side the model backs, and why · Pro
Full Las Vegas Raiders at New Orleans Saints preview →

Los Angeles Rams at Denver Broncos

Sun Sep 27, 8:20 PM ET
Los Angeles Rams at Denver Broncos · Total Points Which side the model backs, and why · Pro
Full Los Angeles Rams at Denver Broncos preview →
How we pick these games

Our model looks at each team's recent form, injuries, rest and the price on offer, and works out how likely each result is. When its number says a bet is more likely to land than the price suggests, the bet makes our list. For each game we show the one main-line bet it likes most. HIGH means it lands about 6 or more times in 10 by our numbers. LEAN means about 4 to 6 times in 10. LONG-SHOT means less than 4 in 10: a bigger payout and a smaller chance. No pick is a sure thing.

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