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Model picks & player props
MLB
Busch Stadium, St. Louis
Outdoor
Wed 15 Apr 2026, 1:15 PM ET
Cleveland Guardians
VS
St. Louis Cardinals

Cleveland Guardians vs St. Louis Cardinals Prediction & Picks

Our model graded 20 markets for Cleveland Guardians vs St. Louis Cardinals and backs Over 9.5 hardest, a lean, and $100 on it returns about $246.

20
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first Free
Over 9.5 total runs
Over 9.5 Total Runs
You bet$10 If it wins$24.60Best price+146
Our confidenceLean
Chance to win52.9%
The price says40.7%

The model graded 20 markets for Cleveland Guardians vs St. Louis Cardinals (MLB) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $246 if it lands. This one is free — every other market and all player props are Pro. Tip-off Wed 15 Apr 2026, 1:15 PM ET at Busch Stadium.

This game's bets

The rest of this game's boardgraded market by market
Total Runs Over 9.5 Lean53% chance +146
Total Runs Members only Lean48% chance Members
Spread Members only Long-shot22% chance Members
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%

Cleveland Guardians and St. Louis Cardinals last met on Wed 15 Apr 2026: St. Louis Cardinals won 5-3. Their next game gets a fresh preview here the moment it is priced. Today's board: every MLB game priced right now.

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Game picks

GOOD PRICE in green
Total Runs
Over
9.5
+ 19 more markets
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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
OverTotal RunsThe model likes this price 🔒 Unlock with Pro
Cleveland GuardiansSpreadThe model likes this price 🔒 Unlock with Pro
Cleveland GuardiansSpreadThe model likes this price 🔒 Unlock with Pro

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Injuries & who's out

Injuries & availability

Cleveland Guardians

  • Colin Holderman RPOut
  • Rhys Hoskins 1BOut
  • Andrew Walters RPOut

St. Louis Cardinals

  • Hunter Dobbins SPOut
  • Richard Fitts SPDay-to-day
  • Masyn Winn SSOut
  • Blaze Jordan 3BOut
  • Joshua Baez LFOut
  • Everson Pereira RFOut
  • Max Rajcic RPOut
Availability updated Oct 1, 4:36PM UTC · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Cleveland Guardians vs St. Louis Cardinals: Ballpark wind and temperature can swing the run total, though the live per-park feed isn't wired into this page yet, and 10 players are listed out or questionable across both sides.
FactorThis fixture
Ballpark weatherWind and temperature at the park move run totals, but our ballpark weather module is pending a file-to-table persistence job.
Availability10 listed out or questionable (see Who's out above)

General rule: wind blowing out and warm air help the ball carry (more runs and home runs), while wind in and cold air suppress scoring; the starting pitchers listed above are the single biggest driver of the run total.

Ballpark weather module pending a file-to-table persistence job (owner). We won't show a wind/temperature number until it's persisted to the database.

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Betting angles

Markets & form
MoneylineSt. Louis CardinalsNo line posted
2-3L5 record
L5 RF3.0L5 RA3.2Home L51-4vs Cleveland Guardians L51-4

St. Louis Cardinals moneyline form: last five 2-3, 3.0 runs/gm.

Run LineSt. Louis Cardinals run lineNo line posted
2-3L5 record
L5 RF3.0L5 RA3.2Home L51-4vs Cleveland Guardians L51-4

St. Louis Cardinals spread form: last five 2-3, 3.0 runs/gm.

Total RunsGame total · St. Louis Cardinals vs Cleveland GuardiansNo line posted

St. Louis Cardinals total runs form: last five 2-3, 3.0 runs/gm.

Team Total RunsSt. Louis Cardinals team totalNo line posted
3.3runs we expect
L5 RF3.0L5 RA3.2Home L51-4vs Cleveland Guardians L51-4

St. Louis Cardinals team total runs form: last five 2-3, 3.0 runs/gm.

Cleveland Guardians @ St. Louis Cardinals — what the model found

Our model graded 20 betting markets for Cleveland Guardians at St. Louis Cardinals — 20 on the game itself and 0 on individual players. One pick is free on this page.

20
Game markets graded

The model checked every betting market for this game and graded 20 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 19 graded calls for this game — with how much to bet on each — are for members.
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Cleveland Guardians vs St. Louis Cardinals — recent results

St. Louis Cardinals have won 1 of their last 5 games; Cleveland Guardians have won 3 of their last 5.

St. Louis Cardinals — last 5
ResultScoreOpponentWhere
L4–6MILAway
L2–3MILAway
L4–8MILAway
L1–2PITAway
W5–1PITAway
Cleveland Guardians — last 5
ResultScoreOpponentWhere
W2–0CHWHome
W9–5CHWAway
W9–3CHWAway
L3–4CHWHome
L0–3CHWHome

Cleveland Guardians vs St. Louis Cardinals — last-5 form comparison

Over their last five games St. Louis Cardinals are scoring 3.4 runs per game (4-1) while Cleveland Guardians are at 4.8 (3-2); St. Louis Cardinals pitchers are allowing 2.0 earned runs per game versus 3.4 for Cleveland Guardians.

3.4
St. Louis Cardinals runs/G
4.8
Cleveland Guardians runs/G
Last 5 gamesSt. Louis CardinalsCleveland Guardians
Runs / game3.44.8
Hits / game5.46.0
Home runs / game1.00.4
Walks drawn / game3.02.0
Batter K / game2.84.2
Earned runs allowed / game2.03.4
Pitching K / game1.44.6
Walks allowed / game1.22.2
L5 record4-13-2

Cleveland Guardians vs St. Louis Cardinals — recent meetings

These two have met 3 times recently: St. Louis Cardinals won 2, Cleveland Guardians won 1.

DateSt. Louis CardinalsCleveland GuardiansWinner
Apr 1553St. Louis Cardinals
Apr 1465St. Louis Cardinals
Apr 1339Cleveland Guardians

Who’s out or in doubt

10 players are listed as out or in doubt for this game.

St. Louis Cardinals
PlayerStatus
Hunter Dobbins SPOUT
Richard Fitts SPDAY-TO-DAY
Masyn Winn SSOUT
Blaze Jordan 3BOUT
Joshua Baez LFOUT
Everson Pereira RFOUT
Max Rajcic RPOUT
Cleveland Guardians
PlayerStatus
Colin Holderman RPOUT
Rhys Hoskins 1BOUT
Andrew Walters RPOUT

The full availability report — with what each missing player means for the bets — is further down this page.

Cleveland Guardians @ St. Louis Cardinals — model preview

Expert analysis and top MLB betting picks for St. Louis Cardinals vs Cleveland Guardians. Includes analysis on key players like NA. Discover MLB predictions, MLB game picks, baseball betting preview, St. Louis Cardinals vs Cleveland Guardians stats and odds.

St. Louis Cardinals vs Cleveland Guardians : Over 8 Total Runs (-133)

Odds available at NA at time of publishing

🔒 The other 4 write-ups for this game — with how much to bet on each — are Pro.
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About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Cleveland Guardians vs St. Louis Cardinals in the MLB. You may also see this matchup written as Guardians vs Cardinals, or as Cardinals vs Guardians. The most recent game between them was Wednesday 15 April 2026 at Busch Stadium. The model has generated 20 game picks for this matchup. Review the picks and historical data above to guide your MLB betting strategy for this matchup.

Cleveland Guardians vs St. Louis Cardinals head-to-head record

Final scores · 12 meetings on record
St. Louis Cardinals 8–4 across the last 12 meetings · these games average 7.9 runs (meetings on record since 2023)

Last meeting: Wed 15 Apr 2026, Cleveland Guardians at St. Louis Cardinals: the Cardinals won 5-3.

DateGameScoreWinner
15 Apr 2026Cleveland Guardians @ St. Louis Cardinals5–3St. Louis Cardinals
14 Apr 2026Cleveland Guardians @ St. Louis Cardinals6–5St. Louis Cardinals
13 Apr 2026Cleveland Guardians @ St. Louis Cardinals3–9Cleveland Guardians
29 Jun 2025St. Louis Cardinals @ Cleveland Guardians0–7St. Louis Cardinals
28 Jun 2025St. Louis Cardinals @ Cleveland Guardians6–9St. Louis Cardinals
27 Jun 2025St. Louis Cardinals @ Cleveland Guardians0–5St. Louis Cardinals
22 Sep 2024Cleveland Guardians @ St. Louis Cardinals2–1St. Louis Cardinals
21 Sep 2024Cleveland Guardians @ St. Louis Cardinals6–5St. Louis Cardinals
20 Sep 2024Cleveland Guardians @ St. Louis Cardinals1–5Cleveland Guardians
28 May 2023St. Louis Cardinals @ Cleveland Guardians4–3Cleveland Guardians

Table shows the last 10 — the record above counts all 12 meetings on file.

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