Arizona Cardinals vs Denver Broncos Prediction & Picks, October 25, 2026

The Arizona Cardinals have shown some promise lately, playing hard and showing they can keep up with tough opponents. Their offense is getting better, and they have a good chance to take down the Denver Broncos at home. With the odds at +195, this bet feels like a solid pick for an underdog that really has a shot. The Broncos have been struggling, which makes this matchup interesting. However, the risk here is that the two teams are closely matched, so it could go either way. Still, the Cardinals have the home field advantage and a chance to surprise everyone with a win.

Arizona Cardinals vs Denver Broncos: Courtland Sutton Over 39.5 Receiving Yards (Alt) (+110)

For this bet to hit, Courtland Sutton needs to rack up over 39.5 receiving yards against the Arizona Cardinals. Sutton has been a solid target for the Denver Broncos, and Arizona's defense has struggled to contain wide receivers. This matchup looks promising since the Broncos are likely to lean on their passing game, especially if they face tough resistance on the ground. There's a decent chance Sutton can get this done, given his recent form and the Cardinals' issues defending against the pass. The biggest risk here is that the two teams are closely matched, so the game could go in unexpected directions. Still, with the right opportunities, Sutton should be able to reach that yardage comfortably.

Arizona Cardinals vs Denver Broncos: Marvin Mims Jr. Over 14.5 Receiving Yards (Alt) (+110)

You can get Marvin Mims Jr. to have over 14.5 receiving yards at +110 odds. Our numbers show he has a good chance to reach this mark against the Arizona Cardinals. The Cardinals have struggled against the pass lately, which could give Mims more opportunities to make catches. While Mims is still a young player and the Broncos have a new quarterback, he has flashed potential in previous games. The biggest risk is that both teams could be closely matched, which might limit scoring chances. Still, with how the Cardinals' defense has performed, this bet looks promising.

Arizona Cardinals vs Denver Broncos: Kendrick Bourne Under 35.5 Receiving Yards (-110)

Kendrick Bourne has been a solid player, but the matchup against the Denver Broncos looks tough for him. The Broncos' defense is known for being strong, and they have shown they can limit opposing receivers. With the game being played in Arizona, Bourne might have a bit of an advantage, but it's not enough to ignore how well the Broncos can shut down passing games. Betting on Bourne to get under 35.5 receiving yards feels right given how close this matchup is. Both teams are similar in skill, so it could go either way. The biggest risk is that if the Cardinals decide to throw more often, Bourne could sneak in a big play. Still, the odds suggest it's likely he will not reach that number today.

That is everything our model likes in this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.