Here are our MLS picks for Saturday 12 September 2026. Our model likes 6 bets here. The one it likes most is Nouhou Tolo (Seattle Sounders FC) Over 0.5 Shots, priced at +110 when we wrote this. Here is the thinking behind each pick, in plain English.
Nouhou Tolo (Seattle Sounders FC) Over 0.5 Shots (+110)
Odds available at FanDuel at time of publishing
As the Seattle Sounders gear up to face the LA Galaxy, all eyes should be on Nouhou Tolo and his propensity to charge forward from the back. While his recent away average of 0.6 shots might not jump off the page, there’s more to his game than meets the eye. With a hit rate of 75% in his last four outings, Tolo has shown he can be a consistent threat, and against a Galaxy side that often leaves space exposed, this could be his moment to shine. We’re betting on him to take at least one shot—after all, his average of 0.8 shots across all matches suggests he’s more than capable. Given LA’s defensive vulnerabilities, expect the Sounders to push forward, giving Tolo the opportunities he needs. If he finds his footing, that Over 0.5 looks like a smart play in this matchup.
Pietro Comuzzo (Torino) Over 0.5 Shots on Target (+900)
Odds available at FanDuel at time of publishing
When Torino hosts AS Roma, all eyes will be on Pietro Comuzzo, a player whose potential is often overshadowed by the more established stars. Although he has yet to hit the target at home this season, his overall game shows promise. Averaging 0.4 shots per match, Comuzzo has the dynamism needed to disrupt Roma’s defense. With an impressive expected goals (xG) model suggesting he could do more, this match might just be the spark he needs. Despite his current hit streak being nonexistent, the odds are in our favor—his last three games saw him find the target once, and there’s always a chance for an uptick in performance at home, where players often thrive. Given AS Roma's defensive vulnerabilities, this could be Comuzzo’s moment to break through. With the line set at just 0.5, the opportunity to capitalize on his potential is too good to pass up.
Ibrahim Mbaye (Senegal) Yes To Be Carded (+1000)
Odds available at DraftKings at time of publishing
As we gear up for the clash between Aston Villa and Nottingham Forest, keep an eye on Ibrahim Mbaye for a potential card. While his recent stats might suggest a quiet game—no yellows or reds in his last five outings—there's more to the story. Playing away often puts players under pressure, especially in a high-stakes environment like Villa Park. Mbaye's role in the squad is crucial, and with the Villa side likely to dominate possession, he may find himself on the defensive more than usual. The expectation of increased fouls in a tight match can lead to the referee reaching for his pocket. The model hints at a 17.5% edge for Mbaye seeing a card, painting a picture of a player who, while not carded recently, could easily find himself in a situation that warrants a booking. Watch for him to step up—sometimes the quiet ones surprise us the most!
Juan Miranda (Bologna) Over 1.5 Shots (+1200)
Odds available at FanDuel at time of publishing
As Juan Miranda steps onto the pitch for Bologna away against Napoli, there's an intriguing opportunity for punters, especially with his total shots line set at 1.5. Now, while his recent form may suggest modest averages—0.4 shots overall and away—there's more to this story. Napoli’s attacking style often leads to chaotic, open games, and Miranda’s position on the flank could see him push forward more than usual. Bologna will look to exploit any defensive gaps, and when they do, expect Miranda to be involved. Given that he has a decent hit rate historically, especially when under pressure, we can see a scenario unfolding where he takes advantage of Napoli’s defensive vulnerabilities. The odds suggest a 7.7% chance, but with the right game context, this feels more optimistic. Look for him to seize this chance and capitalize, making the Over 1.5 shots a compelling play.
Guilherme Biro (Austin FC) Over 2.5 Shots (+1700)
Odds available at FanDuel at time of publishing
As Austin FC heads into Vancouver, keep a close eye on Guilherme Biro. Though his recent form shows a modest average of 0.6 shots away, this matchup offers a chance for him to stretch his legs and find the target more often. Vancouver's defense can be caught off-guard, and with Biro's average of 1.2 shots overall, he’s proven he can create opportunities when the game demands it. Given the Whitecaps' tendency to concede shots, especially against dynamic forwards, this presents a perfect storm for Biro to exceed his usual output. The potential for him to capitalize on defensive lapses means betting on him for over 2.5 shots isn’t just a gamble; it’s a calculated risk that could pay off. With Austin needing to secure points, expect Biro to be more involved in the attack, and don’t be surprised if he surpasses that 2.5 mark.
Odds available at FanDuel at time of publishing
In the upcoming clash between Inter Miami CF and Nashville SC, targeting Jeisson Palacios for Over 0.5 assists feels like a savvy play. While his recent numbers might not jump off the page—averaging 0.2 assists overall and none on the road—there's more to his story. The creativity he brings from the wing can't be understated, especially against a Nashville backline that’s shown vulnerabilities when pressed. Though he hasn’t hit the scoresheet lately, Palacios has the ability to unlock defenses with his passing and positioning. His recent performances suggest he's due for a breakout moment, and with Inter Miami's attacking talent ready to capitalize, this could be the match where he finally registers an assist. Given the circumstances, a bit of faith in his potential to contribute could pay off handsomely. After all, soccer is often about seizing the moment, and this could be Palacios' time to shine.
That is the model's read on today's MLS card. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.
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