Chicago Bears vs New England Patriots Prediction & Picks, October 22, 2026

Betting on Hunter Henry to get over 35.5 receiving yards looks solid. He made nearly 12 yards per catch last season, showing he can rack up yards quickly. The Bears have been more vulnerable to the pass than the run, which could give Henry plenty of chances to get the ball and gain yards. The game is close, though, and the Patriots' quarterback faced fewer extra rushers than the Bears' quarterback, which could affect how quickly plays develop. With both teams performing similarly against the line, it's hard to predict exactly how this will go. However, Henry's ability to gain yards after the catch makes this bet worth a shot.

Chicago Bears vs New England Patriots: Hunter Henry Over 35.5 Receiving Yards (Alt) (-110)

Betting on Hunter Henry to get over 35.5 receiving yards is looking promising. In 2026, he averaged nearly 12 yards per catch, which means he only needs about three receptions to hit this mark. The Bears' defense has had some trouble stopping opposing tight ends, making this a solid matchup for Henry to shine. That said, Henry was only targeted on a small portion of deep passes last season. While he has the skills to produce big plays, the risk is that he might not get enough opportunities to showcase them. Still, with both teams leaning more towards the pass, this could be a good day for Henry to rack up those yards.

Chicago Bears vs New England Patriots: Rome Odunze Over 49.5 Receiving Yards (Alt) (+111)

The odds for Rome Odunze to go over 49.5 receiving yards look pretty appealing. Our numbers see this as a close matchup, and Odunze has been performing well lately, averaging 8.2 fantasy points over his last 15 games. The Bears' quarterback tends to throw more effectively than run, so Odunze could see plenty of action in the air. One risk to keep in mind is that both teams have been facing a decent amount of extra pressure on their quarterbacks, but Odunze's recent form suggests he can handle it. With the Bears at home and their offense leaning on the pass, there's a good chance he hits that yardage mark.

That is everything our model likes in this game. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.