Philadelphia 76ers vs Detroit Pistons Prediction & Picks, October 25, 2026

At the Wells Fargo Center, the 76ers are up against the Pistons, and Paul Reed Jr. is our focus for this bet. He's been playing well, but both teams have solid defense and don't allow many easy points or rebounds. The 76ers give up a decent number of rebounds, but they still limit scoring opportunities, especially from deep. Reed Jr. needs to put together a good game to hit over 23.5 points and rebounds. The risk here is that both teams are close in how they defend against rebounds, which might mean fewer chances for him. Still, our numbers see this as a smart pick to bet under.

Philadelphia 76ers vs Detroit Pistons: Cade Cunningham Under 32.5 Pts + Asts (+120)

Cade Cunningham is facing the Philadelphia 76ers at the Wells Fargo Center, and our numbers see a good chance for him to score under 32.5 points and assists combined. The 76ers are known for letting opponents shoot a lot of three-pointers, but they've also been pretty good at forcing turnovers, which could mean fewer chances for Cade to rack up points and assists. Both teams have similar rebound numbers, so it might be hard for Cade to get those extra opportunities to score or assist. Plus, the matchup could be tight, and that might limit how much he can contribute. Keep this in mind as you consider your bet.

Philadelphia 76ers vs Detroit Pistons: Cade Cunningham Under 14.5 Rebs + Asts (+130)

Cade Cunningham is up against the Philadelphia 76ers at the Wells Fargo Center. The 76ers are pretty tough on defense and have been allowing opponents to grab around 43.7 rebounds a game. Cunningham might find it tricky to rack up his rebounds and assists as the 76ers also force turnovers at a decent rate, making it harder for him to get those extra chances. On top of that, the 76ers let opponents shoot a lot of three-pointers, but they still play strong in the paint. With both teams pretty close in how many rebounds they allow, there's a solid chance Cunningham could finish with less than 14.5 total. Just keep in mind that he could have a breakout game, which is always a possibility.

That is the whole read on this one. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.