Minnesota Vikings vs Indianapolis Colts Prediction & Picks, October 25, 2026

For the Vikings to beat the Colts tonight, Jonathan Taylor needs to catch over 2.5 passes. Taylor has been a key player for the Colts, and with both teams having solid offensive plans, he should have plenty of chances to make some catches. The Vikings' defense has been shaky against good running backs, which gives Taylor a good shot to get the job done. However, the odds are close, so it's not a sure thing. The Colts and Vikings are evenly matched, and that makes it tough to predict. If the game turns into a low-scoring affair, it might limit Taylor's opportunities. Still, given his talent and the way the teams stack up, this bet could pay off.

Minnesota Vikings vs Indianapolis Colts: Jonathan Taylor Yes Anytime Touchdown Scorer (-110)

The odds for Jonathan Taylor to score a touchdown are set at -110, which means it's a solid chance for bettors. Our numbers suggest it's almost a 50/50 shot, making it a decent pick. Taylor has been a key part of the Indianapolis Colts' offense, and they'll need him to step up against the Minnesota Vikings' defense. While the Vikings have shown they can be tough, Taylor's talent and ability to find the end zone give him a real chance to score. The biggest risk here is how closely matched these teams are, so it could go either way. But with Taylor's skill, it's worth a go.

Minnesota Vikings vs Indianapolis Colts: Jonathan Taylor Over 69.5 Rushing Yards (-110)

For Jonathan Taylor to hit over 69.5 rushing yards against the Minnesota Vikings, he just needs to find some room to run. The Vikings have had trouble stopping the run lately, and Taylor is a talented back who can break tackles and make big plays. With the Vikings on their home field, they'll be focused on winning, but that might open up chances for Taylor. Taylor has been playing well and seems to be in good form. The matchup looks favorable since the Vikings' defense has struggled. However, the game could be close, and if the Colts fall behind, they might pass more instead of running. Still, our numbers show he has a good chance to get those yards tonight.

That is our read — no bet on this board is a sure thing. Prices can move before you get on, so check the board at your bookmaker. Bet what you can afford to lose. If betting stops being fun, take a break.