On Thursday 22 October 2026, Sassuolo play Lazio in Serie A. Our model likes 2 bets here. The one it likes most is Both Teams To Score: No, priced at +140 when we wrote this. Here is the thinking behind each pick, in plain English.
Odds correct at time of publishing
As Sassuolo prepares to host Lazio, the signs point towards a match where both teams might struggle to find the net. Sassuolo's recent form at home has been lackluster; they've only found the back of the net twice in their last five home games, averaging 1.8 goals but conceding 2.2. Their xG stats haven’t been impressive either, indicating they’re not creating enough quality chances. On the flip side, Lazio has been solid defensively, especially on the road, allowing just 0.6 goals per game in their last five away fixtures. They come into this match with a strong record against Sassuolo, winning three of their last five encounters. With both teams showing signs of inconsistency in front of goal, betting on “No” for Both Teams to Score seems like a prudent choice in this matchup.
Sassuolo vs Lazio: Lazio Moneyline (+140)
Odds correct at time of publishing
As Lazio heads to Sassuolo on Tuesday, the form book heavily favors the visitors. Lazio's recent run boasts four wins in their last five outings, scoring an impressive 2.4 goals per game while conceding just 0.8. Their away game efficiency has been remarkable, averaging 1.6 goals per match, which bodes well against a Sassuolo side that has struggled defensively, allowing 2.2 goals per game over their last five. Sassuolo's home record reflects inconsistency, with just one win in their past five at home. They’ve averaged only 1.8 goals, and their xG numbers suggest they’re not creating enough clear-cut chances. With Lazio’s attacking prowess and solid form against Sassuolo—winning three of their last five encounters—it's hard to see anything but a Lazio victory here. They have the momentum and the stats to back it up, making them the smart pick for this matchup.
That is how our model reads Sassuolo v Lazio. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.
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