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College football predictions for Thursday, October 22: the model backs East Carolina Pirates

3 college football games on Thursday. The model's strongest pick is East Carolina Pirates +11, a HIGH-confidence call.

By Marcus Cole · Published Oct 21, 12:00 AM ET · Updated Oct 22, 11:30 PM ET

Built from our model's data by our publishing system, checked against our rules. Meet our writers

These were our picks for Thursday, October 22. See today's college football predictions

James Madison Dukes at Appalachian State Mountaineers

Thu Oct 22, 7:00 PM ET
Our pick: James Madison Dukes -12 (they must win by 13 or more; win by exactly 12 and your stake comes back)-111

LEAN — about a 5 in 10 chance by our numbers

Full James Madison Dukes at Appalachian State Mountaineers preview →

Liberty Flames at Kennesaw State Owls

Thu Oct 22, 7:00 PM ET
Our pick: Liberty Flames -9 (they must win by 10 or more; win by exactly 9 and your stake comes back)-110

LEAN — about a 5 in 10 chance by our numbers

Full Liberty Flames at Kennesaw State Owls preview →

East Carolina Pirates at Memphis Tigers

Thu Oct 22, 7:30 PM ET
Top pick: East Carolina Pirates +11 (they can lose by up to 10 and the bet still wins; lose by exactly 11 and your stake comes back)-106

HIGH — about a 6 in 10 chance by our numbers

Full East Carolina Pirates at Memphis Tigers preview →
How we pick these games

Our model looks at each team's recent form, injuries, rest and the price on offer, and works out how likely each result is. When its number says a bet is more likely to land than the price suggests, the bet makes our list. For each game we show the one main-line bet it likes most. HIGH means it lands about 6 or more times in 10 by our numbers. LEAN means about 4 to 6 times in 10. LONG-SHOT means less than 4 in 10: a bigger payout and a smaller chance. No pick is a sure thing.

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